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RAB26 Antibody

  • 中文名稱：
    RAB26兔多克隆抗體
  • 貨號(hào)：
    CSB-PA892347LA01HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: Rat liver tissue
      All lanes: RAB26 antibody at 5.9μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 28, 22 kDa
      Observed band size: 28 kDa
    • IHC image of CSB-PA892347LA01HU diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
    • IHC image of CSB-PA892347LA01HU diluted at 1:200 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) RAB26 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    RAB26
  • 別名：
    CATX-8 antibody; RAB11c antibody; Rab26 antibody; RAB26 member RAS oncogene family antibody; RAB26_HUMAN antibody; Ras related oncogene protein antibody; Ras related protein Rab 26 antibody; Ras-associated protein Rab26 antibody; Ras-related protein Rab-26 antibody; V46133 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human, Rat
  • 免疫原：
    Recombinant Human Ras-related protein Rab-26 protein (1-58AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，RAB26 Antibody (CSB-PA892347LA01HU)，的標(biāo)記方式是Non-conjugated。對(duì)于RAB26 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱 應(yīng)用
    HRP CSB-PA892347LB01HU RAB26 Antibody, HRP conjugated ELISA
    FITC CSB-PA892347LC01HU RAB26 Antibody, FITC conjugated
    Biotin CSB-PA892347LD01HU RAB26 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes. Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different set of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion. Mediates transport of ADRA2A and ADRA2B from the Golgi to the cell membrane. Plays a role in the maturation of zymogenic granules and in pepsinogen secretion in the stomach. Plays a role in the secretion of amylase from acinar granules in the parotid gland.
  • 基因功能參考文獻(xiàn)：
    1. Rab26 selectively directs synaptic and secretory vesicles into preautophagosomal structures. PMID: 25643395
    2. Increased RAB26 expression causes lysosomes to coalesce in a central, perinuclear region within the cell. PMID: 24413166
    3. The small GTPase Rab26 regulates the Golgi to cell surface traffic of alpha(2)-adrenergic receptors, likely through a physical interaction. PMID: 23105096
    4. MIST1 binds to highly conserved CATATG E-boxes to directly activate transcription of 6 genes, including those encoding the small GTPases RAB26 and RAB3D. PMID: 20038531
  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Small GTPase superfamily, Rab family
  • 組織特異性：
    Predominantly expressed in brain.
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 14259

    OMIM: 605455

    KEGG: hsa:25837

    STRING: 9606.ENSP00000210187

    UniGene: Hs.3797



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