在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. RAB11FIP2 Antibody

RAB11FIP2 Antibody

  • 中文名稱：
    RAB11FIP2兔多克隆抗體
  • 貨號：
    CSB-PA437749
  • 規格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from A549 cells, COLO cells, HUVEC cells and MCF-7 cells, using RAB11FIP2 antibody.
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) RAB11FIP2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human RAB11FIP2.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity. Plays an essential role in phagocytosis through a mechanism involving TICAM2, RAC1 and CDC42 Rho GTPases for controlling actin-dynamics.
  • 基因功能參考文獻：
    1. miR-142-3p, a microRNA enriched in exosomes during acute cellular rejection, is transferred to endothelial cells and compromises endothelial barrier function via down-regulation of RAB11FIP2. PMID: 28073833
    2. an interaction of Eps15 and Rab11-FIP2 at the appropriate time and location in polarizing cells is necessary for proper establishment of epithelial polarity. PMID: 28228550
    3. Our data suggested a potential role of Rab11-FIP2 in tumor progression and provided novel insights into the mechanism of how Rab11-FIP2 positively regulated cell migration and invasion in CRC cells. PMID: 26792722
    4. our findings reveal a novel mechanism underlying the role of Rab11-FIP2 in gastric cancer dissemination PMID: 26502090
    5. Rab11-FIP2 binding to MYO5B is essential for vesicular trafficking in Hela and MDCK cells. PMID: 24372966
    6. The recruitment of FIP2 is specific since other members of the Rab11-Family of Interacting Proteins do not associate with the chlamydial inclusions. PMID: 23006599
    7. Rab11A/myosin Vb/Rab11-FIP2 complex frames two late recycling steps of langerin from the ERC to the plasma membrane PMID: 22420646
    8. Rab11-FIP2 functions downstream of Rab11 in endosomal trafficking. PMID: 11994279
    9. Rab11-FIP2 regulates trafficking at multiple points within the apical recycling system of polarized cells PMID: 17626244
    10. the FIP2 C2 mutant caused a failure at the final budding step in the RSV virus life cycle PMID: 18621683
    11. Phosphorylation of Rab11-FIP2 on serine 227 by MARK2 regulates an alternative pathway modulating the establishment of epithelial polarity PMID: 16775013

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell projection, phagocytic cup. Cell membrane; Peripheral membrane protein. Recycling endosome membrane; Peripheral membrane protein. Note=Translocates with RAB11A from the vesicles of the endocytic recycling compartment (ERC) to the plasma membrane.
  • 數據庫鏈接：

    HGNC: 29152

    OMIM: 608599

    KEGG: hsa:22841

    STRING: 9606.ENSP00000347839

    UniGene: Hs.173656



主站蜘蛛池模板： 欧美熟妇性xxxx交潮喷| 777精品出轨人妻国产| 久久这里只精品国产免费9| 国产在线看片无码人精品| 欧美牲交a欧美牲交aⅴ| 欧美熟妇性xxx交潮喷| 国产精品亚洲欧美大片在线看| 欧美变态另类xxxx| 老司机在线精品视频网站 | 亚洲精品美女久久777777| 精产国品一二三产品蜜桃| 呦系列视频一区二区三区 | 免费看国产精品3a黄的视频| 波多野结衣一区二区三区av免费| 青草草在线视频永久免费| 成人网站免费大全日韩国产| 一本一道av中文字幕无码| 无码人妻久久一区二区三区app | 色欲aⅴ 无码| 日本va欧美va欧美va精品| 久久国产成人精品国产成人亚洲 | 日韩免费无码一区二区视频| 一本精品99久久精品77| 无码国产成人午夜在线观看| 超清av在线播放不卡无码| 狠狠亚洲婷婷综合色香五月排名| 无码ol丝袜高跟秘书在线观看| 尤物精品国产第一福利网站| 亚洲精品久久久中文字幕痴女| 肉大捧一进一出免费视频| 一本大道久久香蕉成人网| 亚洲人成网站18禁止一区| 国产精品白丝喷水在线观看| 亚洲中文字幕日产无码成人片 | 中文字幕高清免费日韩视频在线 | 久久综合精品国产二区无码| 成人无码www在线看免费| 亚洲性人人天天夜夜摸18禁止| 精品一区二区三区四区五区六区| 亚洲精品成人无限看| 一本大道在线观看无码一区|