在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

QTRT1 Antibody, Biotin conjugated

  • 中文名稱:
    QTRT1兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA887150LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) QTRT1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    QTRT1
  • 別名:
    FP3235 antibody; Guanine insertion enzyme antibody; qtrt1 antibody; Queuine tRNA ribosyltransferase 1 antibody; Queuine tRNA ribosyltransferase antibody; Queuine tRNA-ribosyltransferase antibody; TGT antibody; TGT, 43 KD subunit antibody; TGT, catalytic subunit antibody; TGT_HUMAN antibody; TGUT antibody; tRNA guanine transglycosylase antibody; tRNA-guanine transglycosylase antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Queuine tRNA-ribosyltransferase catalytic subunit 1 protein (211-403AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming queuine, allowing a nucleophilic attack on the C1' of the ribose to form the product.
  • 基因功能參考文獻:
    1. Homology models of C elegans Tgt and human Tgt suggest that the replacement of Cys158 and Val233 in bacterial Tgt (Zymomonas mobilis) by valine and accordingly glycine in eucaryotic Tgt largely accounts for the different substrate specificities. PMID: 23704982
    2. the inhibition of the human TGT by biopterin, consistent with earlier reports on other eukaryal TGTs, and supportive of the concept that pteridines may regulate eukaryal TGT activity in vivo. PMID: 21640076
    3. phylogenetic and kinetic analyses support the conclusion that all tRNA-guanine transglycosylases have divergently evolved to specifically recognize their cognate heterocyclic substrates. PMID: 21131277
  • 亞細胞定位:
    Cytoplasm. Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic side.
  • 蛋白家族:
    Queuine tRNA-ribosyltransferase family
  • 數據庫鏈接:

    HGNC: 23797

    OMIM: 609615

    KEGG: hsa:81890

    STRING: 9606.ENSP00000250237

    UniGene: Hs.631638



主站蜘蛛池模板: 久久成人国产精品免费| 成人免费午夜无码视频在线播放 | 国产一区二区三区免费高清在线播放| 国产高清在线精品一区| 涩欲国产一区二区三区四区| 天天躁久久躁日日躁| 久久中文字幕人妻av熟女| 野外做受又硬又粗又大视幕| 免费观看在线a毛片| 麻豆tv入口在线看| 夜夜爽日日澡人人添| 久久精品国产只有精品2020| 欧美色欧美亚洲另类二区| 久久亚洲一区二区三区四区| 好紧好湿好黄的视频| 国产在线看片免费视频| 无码人妻丰满熟妇区五十路 | 国产成人综合久久三区| 亚洲国产成人久久综合一区| 久久国产精品久久久久久| 香蕉97超级碰碰碰视频| 国产亚洲精久久久久久无码77777 国产中年熟女高潮大集合 | 中文字幕在线亚洲日韩6页| 中文字幕无码毛片免费看| 色综合久久无码五十路人妻| 欧美三级午夜理伦三级| 亚洲综合欧美在线一区在线播放| 国产精品白丝久久av网站 | 亚洲欧美中文日韩在线视频一 | 69精品国产久热在线观看| 精品无码午夜福利理论片| 豆国产95在线 | 亚洲| 福利姬国产精品一区在线| 嫩草国产福利视频一区二区| 一区三区不卡高清影视| 久久人搡人人玩人妻精品首页| 特大黑人娇小亚洲女| 亚洲中文字幕aⅴ天堂| 国产女厕所盗摄老师厕所嘘嘘| 骚女人干起来舒服视频在线| 中文成人无码精品久久久不卡|