在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. Phospho-HIST1H1B (T154) Antibody

Phospho-HIST1H1B (T154) Antibody

  • 中文名稱：
    磷酸化-HIST1H1B (T154)兔多克隆抗體
  • 貨號：
    CSB-PA010377PA154phHU
  • 規格：
    ￥660
  • 圖片：
    • IHC image of CSB-PA010377PA154phHU diluted at 1:50 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
  • 其他：

產品詳情

  • 產品描述：

    CUSABIO's product CSB-PA010377PA154phHU is a polyclonal antibody raised in rabbits against the synthesized peptide derived from human Histone H1.5 around the phosphorylation T154. This Phospho-HIST1H1B (T154) antibody occurs as an unconjugated IgG. It is only reactive with phosphorylated Histone H1.5 of human-origin. It does not cross-react with non-phosphorylated Histone H1.5 or other phosphorylated forms of Histone H1.5. Validations in ELISA, WB, IF, and ChIP applications of this antibody have been done. The target protein Histone H1.5 is involved in several biological processes, such as cell differentiation, nucleosome spacing and mRNA splicing, and tumorigenesis.

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) HIST1H1B Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    HIST1H1B
  • 別名：
    H1 antibody; H1 histone family member 5 antibody; H1.5 antibody; H15 HUMAN antibody; H15_HUMAN antibody; H1B antibody; H1F5 antibody; H1s 3 antibody; Hist1h1b antibody; Histone 1 H1b antibody; Histone cluster 1 H1b antibody; Histone H1.5 antibody; Histone H1a antibody; Histone H1b antibody; Histone H1s 3 antibody; MGC126630 antibody; MGC126632 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Peptide sequence around site of Phospho-Thr (154) derived from Human Histone H1.5
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Histone H1 protein binds to linker DNA between nucleosomes forming the macromolecular structure known as the chromatin fiber. Histones H1 are necessary for the condensation of nucleosome chains into higher-order structured fibers. Acts also as a regulator of individual gene transcription through chromatin remodeling, nucleosome spacing and DNA methylation.
  • 基因功能參考文獻：
    1. Data indicate that normal ovarian tissues strongly expressed histone H1.5, whereas ovarian granulosa cell tumors (GCTs) weakly expressed this protein; in contrast, PLZF protein expression was not significantly different between both study groups. PMID: 25023763
    2. Statistically significant differences in staining patterns were found for histone H1.5, distinguishing leiomyosarcomas from leiomyomas. PMID: 24784718
    3. Promyelocytic leukemia zinc finger and histone H1.5 differentially stain low- and high-grade pulmonary neuroendocrine tumors PMID: 23416030
    4. FoxP3 interacts with H1.5 to alter its binding to target genes to modulate their expression and to program Treg function. PMID: 21654845
    5. the mode of the chromatin fiber compaction changes depending both on salt environment and linker histone H1 PMID: 16185066
    6. Phosphorylation of human H1 variants occurs nonrandomly during both interphase and mitosis and distinct serine- or threonine-specific kinases are involved in different cell cycle phases. PMID: 16377619
    7. Phosphorylation at threonine 10 appears in prometaphase and disappears in telophase, and that this hyperphosphorylated form of H1.5 is mainly chromatin-bound in metaphase when chromatin condensation is maximal. PMID: 19136008

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Chromosome. Note=According to PubMed:15911621 more commonly found in heterochromatin. According to PubMed:10997781 associates with actively transcribed chromatin and not heterochromatin.
  • 蛋白家族：
    Histone H1/H5 family
  • 組織特異性：
    Ubiquitous. Expressed in the majority of the cell lines tested and in testis.
  • 數據庫鏈接：

    HGNC: 4719

    OMIM: 142711

    KEGG: hsa:3009

    STRING: 9606.ENSP00000330074

    UniGene: Hs.131956



主站蜘蛛池模板： 中文无码vr最新无码av专区| 夜夜天天噜狠狠爱2019| 国产午夜精品av一区二区麻豆| 亚洲狠狠婷婷综合久久| 高清无码一区二区在线观看吞精| 久久婷婷人人澡人人爽人人喊| 少妇激情作爱视频| 一二三四在线视频社区3| 国产男女无遮挡猛进猛出 | 精品www日韩熟女人妻| 欧洲熟妇色xxxxx视频| 美女露出奶头扒开尿口视频直播| 国产成人无码av一区二区在线观看| 好男人社区资源| 国产亚洲福利在线视频| 中文无码精品a∨在线| 黑人巨大精品欧美| 日韩精品无码一区二区| 4480yy私人精品国产| 五 月 丁 香 综合中文| 欧美奶涨边摸边做爰视频| 一本久道久久综合狠狠爱| 国产永久免费观看的黄网站| 久久九九国产精品怡红院| 国产欧美高清在线观看| 无码专区 人妻系列 在线| 久久精品亚洲乱码伦伦中文| 新版天堂资源中文8在线| 人妻奶水人妻系列| 浪荡女天天不停挨cao日常视频| 午夜福利视频1692| 67194成是人免费无码| 天堂mv在线mv免费mv香蕉| 国产农村乱子伦精品视频| 免费无码一区二区三区a片百度| 午夜精品久久久久久久久| 在线天堂资源www在线污| 中国6一12呦女精品| 久久精品国产精品| 久久国产色欲av38| 老色鬼永久精品网站|