在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Pcsk1 Antibody, FITC conjugated

Rare Species
  • 中文名稱:
    Pcsk1兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA017640LC01RA
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Rattus norvegicus (Rat) Pcsk1 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    Pcsk1
  • 別名:
    Pcsk1 antibody; Bdp antibody; Nec-1 antibody; Nec1Neuroendocrine convertase 1 antibody; NEC 1 antibody; EC 3.4.21.93 antibody; Prohormone convertase 1 antibody; Proprotein convertase 1 antibody; PC1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Rat
  • 免疫原:
    Recombinant Rat Neuroendocrine convertase 1 protein (111-752AA)
  • 免疫原種屬:
    Rattus norvegicus (Rat)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Substrates include POMC, renin, enkephalin, dynorphin, somatostatin, insulin and AGRP.
  • 基因功能參考文獻:
    1. macrophages from PC1/3 KO mice and rat PC1/3-KD NR8383 macrophages secreted more pro-inflammatory cytokines such as TNF-alpha, IL6, IL1alpha and CXCL2. PMID: 26778167
    2. PC1/3 as an important regulator of vesicle trafficking and secretion in macrophages. PMID: 23637853
    3. Chronic ethanol exposure decreases prohormone convertase (pc1/3) immunoreactivity in brain. PMID: 23050949
    4. catalytic and P domains contribute to the folding and thermodynamic stability of the convertases through reciprocal hydrophobic interactions (prohormone convertase 3 [pc3/pc1]) PMID: 12721373
    5. The prohormone convertase (PC) enzyme PC1 together with PC2 and PC5 may represent a redundant system to ensure production of biologically active cholecystokinin in rat brain. PMID: 14608596
    6. proGHRH is initially cleave by furin at preproGHRH29-30, followed by a second cleavage at preproGHRH74 primarily by PC1 to generate GHRH and GHRH-RP peptides, respectively. PMID: 15146101
    7. Leptin regulates hypothalamic PC1 expression and requires prohormone processing into mature peptides. PMID: 15286802
    8. Prohormone-convertase 1 processing enhances post-Golgi sorting of prothyrotropin-releasing hormone-derived peptides PMID: 16204236
    9. the prohormone convertase cleavage site within the alpha-helix mediates sorting of the neuronal and endocrine polypeptide VGF into the regulated secretory pathway PMID: 16221685
    10. The observed decrease in CCK seen with these RNAi treatments further supports a role for PC1 in CCK processing in these cells PMID: 16274843
    11. Agouti-related protein is posttranslationally cleaved by proprotein convertase 1 to generate agouti-related protein (AGRP)83-132. PMID: 16384863
    12. These data indicate that the transmembrane domain of PC3 plays a key role in sorting the enzyme to the regulated secretory pathway. PMID: 17240044
    13. Ontogeny of ghrelin, obestatin, preproghrelin, and prohormone convertases in rat pancreas and stomach. PMID: 18784614

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasmic vesicle, secretory vesicle. Note=Localized in the secretion granules.
  • 蛋白家族:
    Peptidase S8 family, Furin subfamily
  • 數據庫鏈接:


主站蜘蛛池模板: 99久久er这里只有精品18| 国产乱色精品成人免费视频| 亚洲 日韩 欧美 成人 在线观看| 久久久久国产精品人妻aⅴ天堂| 五月色婷婷丁香无码三级| 欧美性猛交久久久乱大交小说| 国产手机在线αⅴ片无码观看| 亚洲成在人线免费观看| 日韩人妻无码精品专区综合网| 欧美最猛黑人xxxxx猛交| 亚洲国产成人一区二区精品区| 97视频精品全国免费观看| 久久只有这里有精品4| 色老99久久精品偷偷鲁| 自拍偷自拍亚洲精品播放| 久久久这里只有免费精品| 麻豆果冻精东九一传媒mv| 亚洲精品久久久av无码专区| 国产欧美日韩综合精品一区二区| а√中文在线资源库| 人妻影音先锋啪啪av资源| 国产精品一区二区高清在线| 无套内谢老熟女| 中文国产乱码在线人妻一区二区| 国产欧美在线亚洲一区| 无码国产精品一区二区免费模式| 97一区二区国产好的精华液| 国产日产欧产精品精品app| 久久www免费人成_看片中文| 国产麻豆精品一区| 99久久国产露脸精品国产麻豆 | 午夜免费国产体验区免费的 | 草草浮力地址线路①屁屁影院 | 国产亚洲精品岁国产微拍精品 | 午夜精品电影你懂的 | 玩两个丰满老熟女| 潮喷失禁大喷水无码| 久久久精品妇女99| 精品国产一区二区三区久久久狼| 日本乱妇乱子视频网站-百度| 99精品视频一区在线观看|