在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PTPRF Antibody, Biotin conjugated

  • 中文名稱:
    PTPRF兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA019053LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PTPRF Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    FLJ43335 antibody; FLJ45062 antibody; FLJ45567 antibody; LAR antibody; LAR protein antibody; LARFN5C antibody; LARS antibody; LCA homolog antibody; Leukocyte antigen related (LAR) PTP receptor antibody; Leukocyte antigen related antibody; Leukocyte antigen related PTP receptor antibody; Leukocyte antigen related tyrosine phosphatase antibody; Leukocyte common antigen related antibody; Protein Tyrosine Phosphatase Receptor Type F antibody; Protein tyrosine phosphatase receptor type F polypeptide antibody; Ptprf antibody; PTPRF protein antibody; PTPRF_HUMAN antibody; Receptor linked protein tyrosine phosphatase LAR antibody; Receptor type tyrosine protein phosphatase F antibody; Receptor type tyrosine protein phosphatase F precursor antibody; Receptor-type tyrosine-protein phosphatase F antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Receptor-type tyrosine-protein phosphatase F protein (688-970AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Possible cell adhesion receptor. It possesses an intrinsic protein tyrosine phosphatase activity (PTPase) and dephosphorylates EPHA2 regulating its activity.; The first PTPase domain has enzymatic activity, while the second one seems to affect the substrate specificity of the first one.
  • 基因功能參考文獻:
    1. transferred nuclear Overhauser effects (trNOEs) have been employed in the docking program HADDOCK to generate models for the LAR-fondaparinux complex. These models are further analyzed by postprocessing energetic analysis to identify key binding interactions. PMID: 29570275
    2. PTPRF may have value as a predictive marker to identify which patients can obtain the greatest benefit from erlotinib in the post-first-line setting. PMID: 26291013
    3. Homozygous truncating PTPRF mutation causes athelia. PMID: 24781087
    4. PTPRF is down-regulated in hepatocellular carcinoma-facilitated tumor development. PMID: 24470239
    5. Interaction between the tripartite NGL-1, netrin-G1 and LAR adhesion complex promotes development of excitatory synapses. PMID: 23986473
    6. LAR functions as a negative regulator of adipogenesis. PMID: 19910497
    7. regulation of expression by cell density through functional E-cadherin complexes PMID: 12095414
    8. LAR PTPase domains play distinct functional roles in phosphorylation and dephosphorylation PMID: 12496362
    9. LAR as a crucial regulator of the sensitivity of two key insulin signalling pathways to insulin PMID: 15896785
    10. Results identify a protein tyrosine phosphatase as a potential substrate of TACE and describe proteolytic processing of PTP-LAR as a means of regulating phosphatase activity downstream and thus under the control of EGFR-mediated signaling pathways. PMID: 16478662
    11. Regulated degradation of liprinalpha1 is important for proper LAR receptor distribution, and could provide a mechanism for localized control of dendrite and synapse morphogenesis by activity and CaMKII. PMID: 17419996
    12. LAR and Src are identified as Death-associated protein kinase (DAPK) regulators through their reciprocal modification of DAPK Y491/492 residues and establishes a functional link of this DAPK-regulatory circuit to tumor progression. PMID: 17803936

    顯示更多

    收起更多

  • 相關疾病:
    Aplasia or hypoplasia of the breasts and/or nipples 2 (BNAH2)
  • 亞細胞定位:
    Membrane; Single-pass type I membrane protein.
  • 蛋白家族:
    Protein-tyrosine phosphatase family, Receptor class 2A subfamily
  • 數據庫鏈接:

    HGNC: 9670

    OMIM: 179590

    KEGG: hsa:5792

    STRING: 9606.ENSP00000353030

    UniGene: Hs.272062



主站蜘蛛池模板: 成人做爰视频www网站小优视频| 亚洲女教师丝祙在线播放| 亚洲中文字幕精品久久久久久动漫| 在线亚洲日产一区二区| 任我橹这里只有精品 在线视频| 国产卡一卡二卡三精品| 中文字幕人妻熟女人妻| 全黄性性激高免费视频| 久久久久国精品产熟女久色| 亚洲中文字幕av无码区| 九九热爱视频精品视频16| 国产精品毛多多水多| 久久精品国产色蜜蜜麻豆| 强伦人妻一区二区三区视频18| 亚洲a∨国产av综合av网站| 成人网站www污污污网站| 国产人妻久久精品二区三区老狼| 少妇内射高潮福利炮| 无码专区 人妻系列 在线| 亚洲人成无码网www动漫| 99e热久久免费精品首页| 国产精品国产高清国产av| 97视频在线观看播放| 国产情侣真实54分钟在线| 性欧美俄罗斯乱妇| 大地资源在线观看官网第三页| 成人无码一区二区三区| 精品无码av无码专区| 午夜爱爱免费视频体验区| 中文在线www天堂网| 青青久在线视频免费观看| 四虎国产精品永久在线国在线| 久久精品高清一区二区三区| 国产伦精品一区二区三区免.费| 国产无遮挡裸体免费视频在线观看| 狠狠五月深爱婷婷网| 日韩免费无码人妻波多野| 亚洲a∨无码一区二区三区 | 久久国产乱子伦精品免费午夜| 137日本免费肉体摄影| 国产午夜高潮熟女精品av软件 |