在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PTPRE Antibody

PTPRE Antibody

  • 中文名稱：
    PTPRE兔多克隆抗體
  • 貨號：
    CSB-PA246334
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using CSB-PA246334(PTPRE Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using CSB-PA246334(PTPRE Antibody) at dilution 1/10, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PTPRE
  • 別名：
    PTPRE; Receptor-type tyrosine-protein phosphatase epsilon; Protein-tyrosine phosphatase epsilon; R-PTP-epsilon
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human PTPRE
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:5000
    IHC 1:15-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function.; Isoform 2 acts as a negative regulator of insulin receptor (IR) signaling in skeletal muscle. Regulates insulin-induced tyrosine phosphorylation of insulin receptor (IR) and insulin receptor substrate 1 (IRS-1), phosphorylation of protein kinase B and glycogen synthase kinase-3 and insulin induced stimulation of glucose uptake.; Isoform 1 and isoform 2 act as a negative regulator of FceRI-mediated signal transduction leading to cytokine production and degranulation, most likely by acting at the level of SYK to affect downstream events such as phosphorylation of SLP76 and LAT and mobilization of Ca(2+).
  • 基因功能參考文獻：
    1. these data demonstrate that HCV infection reduces PTPRE expression in the liver and peripheral blood mononuclear cell sof infected humans PMID: 28235043
    2. Studies indicate that RAD50 and PTPRE of crude associations with asthma at a Bonferroni-corrected level of significance, while IL4R, CCL5 and TBXA2R of nominal significance. PMID: 21734400
    3. Transfection of cells with different PTPepsilon constructs and activator protein-1 reporter gene indicates that the catalytic activity of PTPepsilon is involved in the regulation of the mitogen-activated protein kinase cascade. PMID: 12121439
    4. Characterization, expression and functional aspects of an alternative spliced isoform of protein tyrosine phosphatase epsilon PMID: 12193229
    5. Functions to prevent inappropriate activation and to terminate prolonged, rather than acute, activation of ERK in the cytosol. PMID: 12754301
    6. cyt-PTP epsilon is dimerized and phosphorylated in the absence of direct interaction between the PTP and extracellular molecules PMID: 12861030
    7. Transgenic mice overexpressing catalytically inactive transmembrane protein tyrosine phosphatase epsilon provide unexpected insight into the cell-cell interactions that occur between oligodendrocytes and the cells which they myelinate. PMID: 15390114
    8. Protein-tyrosine phosphatase epsilon regulates Shc signaling in a kinase-specific manner: increasing coherence in tyrosine phosphatase signaling PMID: 18093973

    顯示更多

    收起更多

  • 亞細胞定位：
    [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cytoplasm.; [Isoform 3]: Cytoplasm.
  • 蛋白家族：
    Protein-tyrosine phosphatase family, Receptor class 4 subfamily
  • 組織特異性：
    Expressed in giant cell tumor (osteoclastoma rich in multinucleated osteoclastic cells).
  • 數據庫鏈接：

    HGNC: 9669

    OMIM: 600926

    KEGG: hsa:5791

    STRING: 9606.ENSP00000254667

    UniGene: Hs.127022



主站蜘蛛池模板： 婷婷四房综合激情五月在线| 日本在线视频www鲁啊鲁| 成人性做爰aaa片免费| 国产精品久久久久久亚洲| 日本欧美大码a在线观看| 成人亚洲a片v一区二区三区蜜臀| 波多野结衣爽到高潮大喷| 少妇爱做高清免费视频| 99在线精品视频观看免费| 少妇无码太爽了不卡视频在线看| 日韩精品一区二区三区免费视频| 亚洲乱码无码永久不卡在线| 色综合av综合无码综合网站| 日韩在线一区二区不卡视频| 成人影院永久免费观看网址| 正在播放熟妇群老熟妇456 | 麻豆亚洲一区| 国产精品无码无卡无需播放器| a毛看片免费观看视频| 亚洲男人的天堂在线va| 亚洲午夜高清国产拍| 欧美成人一区二区三区在线观看 | 国产乱人伦av在线无码| 国产精品亚洲成在人线| 久久久av男人的天堂| 国产精品毛片更新无码| 202丰满熟女妇大| а天堂中文官网| 亚洲人成在线观看网站不卡| 久久99国产综合精品女同| 成人亚洲欧美激情在线电影| av人摸人人人澡人人超碰妓女| 好男人www社区| 亚洲国产精品久久久天堂麻豆宅男 | 欧美成人午夜精品久久久| 国产综合精品| 国产午夜片无码区在线观看爱情网 | 国产麻豆精品精东影业av网站| 午夜色大片在线观看| 国产精品无码不卡一区二区三区| 国产精品亚洲一区二区三区喷水|