在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PTGES2 Antibody

PTGES2 Antibody

  • 中文名稱：
    PTGES2兔多克隆抗體
  • 貨號(hào)：
    CSB-PA018977GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    C9orf15 antibody; FLJ14038 antibody; Gamma interferon activated transcriptional element binding factor 1 antibody; GATE binding factor 1 antibody; GBF 1 antibody; GBF1 antibody; Membrane associated prostaglandin E synthase 2 antibody; MGC11289 antibody; Microsomal prostaglandin E synthase 2 antibody; mPGES 2 antibody; mPGES-2 antibody; PGES2 antibody; PGES2_HUMAN antibody; Prostaglandin E synthase 2 antibody; Prostaglandin E synthase 2 truncated form antibody; PTGES 2 antibody; PTGES2 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PTGES2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Isomerase that catalyzes the conversion of PGH2 into the more stable prostaglandin E2 (PGE2) (in vitro). The biological function and the GSH-dependent property of PTGES2 is still under debate. In vivo, PTGES2 could form a complex with GSH and heme and would not participate in PGE2 synthesis but would catalyze the degradation of prostaglandin E2 H2 (PGH2) to 12(S)-hydroxy-5(Z),8(E),10(E)-heptadecatrienoic acid (HHT) and malondialdehyde (MDA).
  • 基因功能參考文獻(xiàn)：
    1. Four single nucleotide polymorphisms in two genes in the PGE2 family, PTGES2 and PTGER4, were significantly associated with primary graft dysfunction after lung transplantation. PMID: 24467603
    2. high immunoreactivity of mPGES-2 in pyramidal neurons of AD brains indicates that it might have a potential role in the functional replacement of cytosolic PGES or inactive mPGES-1 in later stages of Alzheimer disease PMID: 19664621
    3. Up-regulation of prostaglandin E2 synthesis by interleukin-1beta in human orbital fibroblasts involves coordinate induction of prostaglandin-endoperoxide H synthase-2 and glutathione-dependent prostaglandin E2 synthase expression PMID: 11847219
    4. role in regulating interferon-gamma-dependent gene expression PMID: 12050152
    5. 110Cys is essential in the active site of membrane-associated prostaglandin E synthase-2 PMID: 12804604
    6. Transactivators GBF1 and CCAAT/enhancer-binding protein-beta physically interact to induce interferon-gamma-regulated transcription; a 37-aa long peptide derived from the GBF1 protein can associate with C/EBP-beta in an IFN-inducible manner. PMID: 15879117
    7. alphaTOS inhibits COX activity, thereby inhibiting PGE2 production in human lung epithelial cells PMID: 16714329
    8. study obtained evidence from two Caucasian study populations that the His298-allele of PTGES2 Arg298His confers to reduced risk of type 2 diabetes PMID: 17566096
    9. Carbonyl reductase-1 (CBR1), microsomal prostaglandin E synthase-1 and 2 (mPGES-1, mPGES-2), cytosolic prostaglandin E synthase (cPGES), aldoketoreductase (AKR1C1) and prostaglandin F synthase (AKR1C3) were all expressed in hair follicles. PMID: 17697149
    10. risk-reducing effects of the minor His allele of the prostaglandin E synthase 2 (PTGES2) Arg298His polymorphism could be mediated partly by lowered body mass index (BMI) PMID: 17979097
    11. all three terminal prostaglandin synthases, mPGES-1, mPGES-2, and cPGES, are over-expressed in human gliomas PMID: 19347995
    12. A marginal but significant influence of the PTGES2 298H single nucleotide polymorphism on BMI was found in a large population-based study. PMID: 19371221
    13. These results indicate that mPGES-1 and mPGES-2 may each play a role in colorectal cancer progression. PMID: 19412621

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Golgi apparatus membrane; Single-pass membrane protein.; [Prostaglandin E synthase 2 truncated form]: Cytoplasm, perinuclear region.
  • 蛋白家族：
    GST superfamily
  • 組織特異性：
    Widely expressed. Expressed in the heart, including apex, inter-ventricular septum, both atria and ventricles, but not in the aorta. Also expressed in fetal heart. Detected in various regions of the brain: cerebellum; occipital, frontal and parietal lobes
  • 數(shù)據(jù)庫鏈接：

    HGNC: 17822

    OMIM: 608152

    KEGG: hsa:80142

    STRING: 9606.ENSP00000345341

    UniGene: Hs.495219



主站蜘蛛池模板： 18禁止午夜福利体验区| 四虎永久在线精品免费网址| 无人区码一码二码三码区别新月| 国产男女猛烈视频在线观看| 欧美日韩国产综合新一区| 色橹橹欧美在线观看视频高清| 欧美人与禽zoz0性伦交| 免费无码黄动漫十八禁| 丝袜高潮流白浆潮喷在线播放| 精品1卡二卡三卡四卡老狼| 老熟妇高潮喷了╳╳╳| 国产精品亚洲а∨天堂免下载| 亚洲成av人片在www鸭子| 久久精品久久久久观看99水蜜桃 | 亚洲精品一线二线三线无人区| 国产精品爆乳在线播放第一人称| 亚洲欧美另类成人综合图片| 无码人妻少妇精品无码专区漫画| 国产男女猛烈无遮挡免费视频| 啦啦啦中文在线观看日本| 中文人妻熟妇乱又伦精品| 亚洲精品无码久久久久不卡| 中文字幕亚洲无线码| 国产女人爽的流水毛片| 婷婷丁香五月天综合东京热| 少妇高潮大叫好爽| 久碰久摸久看视频在线观看| 日本在线看片免费人成视频| 波多野结衣超清无码专区| 久久精品国自产拍| 久久综合久色欧美综合狠狠| 欧美精品18videosex性欧美| 无码三级国产三级在线电影 | 欧洲熟妇色xxxx欧美老妇多毛| 亚州少妇无套内射激情视频| 四虎亚洲精品高清在线观看| 四虎成人精品永久在线视频| 国产一区二区精品丝袜| 亚洲va天堂va欧美片a在线| 天堂资源在线www在线观看| 伊伊人成亚洲综合人网7777|