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PTDSS1 Antibody

  • 中文名稱(chēng)：
    PTDSS1兔多克隆抗體
  • 貨號(hào)：
    CSB-PA04305A0Rb
  • 規(guī)格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in: 293T whole cell lysate(20μg), K562 whole cell lysate(20μg), HepG2 whole cell lysate(20μg), MCF7 whole cell lysate(20μg
      All lanes: PTDSS1 antibody at 1:1000
      Secondary
      Goat polyclonal to rabbit IgG at 1/20000 dilution
      Predicted band size: 56,39,35 kDa
      Observed band size: 35 kDa
      Exposure time: 60s
    • IHC image of CSB-PA04305A0Rb diluted at 1:150 and staining in paraffin-embedded humanpancreatic cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. Secondary antibody only control: uses 1% BSA instead of primary antibody
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱(chēng)：
    Rabbit anti-Homo sapiens (Human) PTDSS1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PTDSS1 antibody; KIAA0024 antibody; PSSA antibody; Phosphatidylserine synthase 1 antibody; PSS-1 antibody; PtdSer synthase 1 antibody; EC 2.7.8.29 antibody; Serine-exchange enzyme I antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Phosphatidylserine synthase 1 protein (1-35AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated

    本頁(yè)面中的產(chǎn)品，PTDSS1 Antibody (CSB-PA04305A0Rb)，的標(biāo)記方式是Non-conjugated。對(duì)于PTDSS1 Antibody，我們還提供其他標(biāo)記。見(jiàn)下表：

    可提供標(biāo)記
    標(biāo)記方式 貨號(hào) 產(chǎn)品名稱(chēng) 應(yīng)用
    HRP CSB-PA04305B0Rb PTDSS1 Antibody, HRP conjugated ELISA
    FITC CSB-PA04305C0Rb PTDSS1 Antibody, FITC conjugated
    Biotin CSB-PA04305D0Rb PTDSS1 Antibody, Biotin conjugated ELISA
  • 克隆類(lèi)型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:3000
    IHC 1:100-1:300
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Catalyzes a base-exchange reaction in which the polar head group of phosphatidylethanolamine (PE) or phosphatidylcholine (PC) is replaced by L-serine. Catalyzes mainly the conversion of phosphatidylcholine. Also converts, in vitro and to a lesser extent, phosphatidylethanolamine.
  • 基因功能參考文獻(xiàn)：
    1. RYR2, PTDSS1 and AREG are autism susceptibility genes that are implicated in a Lebanese population-based study of copy number variations in this disease. PMID: 26742492
    2. PSS1 mutations not only affect cellular PS levels and distribution but also lead to a more complex imbalance in lipid homeostasis by disturbing PI4P metabolism. PMID: 27044099
    3. Gain-of-function missense mutations in the phosphatidylserine synthase 1 (PTDSS1) gene cause Lenz-Majewski syndrome. PMID: 24241535
    4. Purification and characterization of human phosphatidylserine synthases 1 and 2. PMID: 19014349
  • 相關(guān)疾病：
    Lenz-Majewski hyperostotic dwarfism (LMHD)
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Multi-pass membrane protein.
  • 蛋白家族：
    Phosphatidyl serine synthase family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9587

    OMIM: 151050

    KEGG: hsa:9791

    STRING: 9606.ENSP00000430548

    UniGene: Hs.292579



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