在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PSMC3 Antibody

  • 中文名稱:
    PSMC3兔多克隆抗體
  • 貨號(hào):
    CSB-PA040034
  • 規(guī)格:
    ¥1090
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
    PSMC3
  • 別名:
    26S protease regulatory subunit 6A antibody; 26S proteasome AAA-ATPase subunit RPT5 antibody; Human immunodeficiency virus tat transactivator binding protein 1 antibody; MGC8487 antibody; Proteasome (prosome macropain) 26S subunit ATPase 3 antibody; Proteasome 26S ATPase subunit 3 antibody; Proteasome 26S subunit ATPase 3 antibody; Proteasome subunit P50 antibody; PRS6A_HUMAN antibody; PSMC 3 antibody; PSMC3 antibody; Tat binding protein 1 antibody; TAT-binding protein 1 antibody; TBP-1 antibody; TBP1 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PSMC3.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    WB, IHC, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
  • 基因功能參考文獻(xiàn):
    1. These data suggest the existence of a negative feedback loop involving Akt/PKB that might act as a sensor to modulate TBP-1 levels in proliferating cells. PMID: 21991300
    2. 19S ATPase S6b (S6'/TBP1) binds CIITApIV in an S6a-dependent fashion and has effects similar to S6a on CIITApIV histone acetylation. PMID: 19853614
    3. role in E3 ubiquitin ligase function of the von Hippel-Lindau protein PMID: 14556007
    4. molecular modeling of DNA:TATA element binding protein (TBP) interactions after treatment with 2-Chloro-2'-deoxyadenosine PMID: 14610662
    5. Tat-binding protein-1 binds to human ARF tumor suppressor and has a role in control of cell proliferation PMID: 14665636
    6. In normal cells, unmodified S12 associates with the 26S proteasome, while modified S12-M does not. PMID: 15221960
    7. The stabilization effect exerted by TBP-1 requires an intact N-terminal 39 amino acids in ARF and occurs independently from N-terminal ubiquitination of the protein. PMID: 17334400
    8. Heplipin induced KG-1 cell apoptosis is related with Wntl3 and ATPase3. PMID: 17649721
    9. findings suggest that a component of 19S regulatory particles directly binds AR and might participate in AR-mediated transcriptional activation in cooperation with TBPIP. PMID: 19325002

    顯示更多

    收起更多

  • 亞細(xì)胞定位:
    Cytoplasm. Nucleus.
  • 蛋白家族:
    AAA ATPase family
  • 數(shù)據(jù)庫(kù)鏈接:

    HGNC: 9549

    OMIM: 186852

    KEGG: hsa:5702

    STRING: 9606.ENSP00000298852

    UniGene: Hs.250758



主站蜘蛛池模板: 亚洲一区二区三区在线播放无码| 亚洲电影在线观看| 国产成人无码区免费内射一片色欲| 亚洲欧美日本国产专区一区| 国产成人剧情av麻豆果冻| 久久不见久久见www电影免费| 熟女人妻aⅴ一区二区三区60路| 人妻巨大乳一二三区| 人人妻人人添人人爽欧美一区| 国产欧美在线一区二区三| 国产av巨作丝袜秘书| 亚洲天天做日日做天天谢日日欢| 久久99精品久久久久久噜噜| 日本免码va在线看免费| 国产精品99爱免费视频| 337p日本欧洲亚洲大胆| 国产精品久久婷婷六月丁香| 男人和女人高潮做爰视频| 免费观看成人欧美www色| 狠狠躁夜夜躁人人爽天天天天97 | 国产yw8825免费观看网站| 国产成人啪精品视频免费视频| 中国真实偷乱视频| 伊人情人综合网| 精品无码欧美黑人又粗又| 亚洲精品国产成人精品软件| 扒开女人内裤猛进猛出免费视频| 亚洲欧美中文字幕5发布| 啪啪后入内射日韩| 日韩吃奶摸下aa片免费观看| 久久精品一区二区三区av| 日韩一区二区三区北条麻妃| 色综合亚洲一区二区小说性色aⅴ| 激情人妻另类人妻伦| 亚洲ⅴ国产v天堂a无码二区| 国产片a国产片免费看视频| 久久久久成人片免费观看蜜芽| 中国精品少妇hd| 亚洲精品无码成人片| 免费无码又爽又刺激聊天app| 国产欧美精品aaaaaa片|