在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PSMC3 Antibody

PSMC3 Antibody

  • 中文名稱：
    PSMC3兔多克隆抗體
  • 貨號(hào)：
    CSB-PA040034
  • 規(guī)格：
    ￥1090
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PSMC3
  • 別名：
    26S protease regulatory subunit 6A antibody; 26S proteasome AAA-ATPase subunit RPT5 antibody; Human immunodeficiency virus tat transactivator binding protein 1 antibody; MGC8487 antibody; Proteasome (prosome macropain) 26S subunit ATPase 3 antibody; Proteasome 26S ATPase subunit 3 antibody; Proteasome 26S subunit ATPase 3 antibody; Proteasome subunit P50 antibody; PRS6A_HUMAN antibody; PSMC 3 antibody; PSMC3 antibody; Tat binding protein 1 antibody; TAT-binding protein 1 antibody; TBP-1 antibody; TBP1 antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PSMC3.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
  • 基因功能參考文獻(xiàn)：
    1. These data suggest the existence of a negative feedback loop involving Akt/PKB that might act as a sensor to modulate TBP-1 levels in proliferating cells. PMID: 21991300
    2. 19S ATPase S6b (S6'/TBP1) binds CIITApIV in an S6a-dependent fashion and has effects similar to S6a on CIITApIV histone acetylation. PMID: 19853614
    3. role in E3 ubiquitin ligase function of the von Hippel-Lindau protein PMID: 14556007
    4. molecular modeling of DNA:TATA element binding protein (TBP) interactions after treatment with 2-Chloro-2'-deoxyadenosine PMID: 14610662
    5. Tat-binding protein-1 binds to human ARF tumor suppressor and has a role in control of cell proliferation PMID: 14665636
    6. In normal cells, unmodified S12 associates with the 26S proteasome, while modified S12-M does not. PMID: 15221960
    7. The stabilization effect exerted by TBP-1 requires an intact N-terminal 39 amino acids in ARF and occurs independently from N-terminal ubiquitination of the protein. PMID: 17334400
    8. Heplipin induced KG-1 cell apoptosis is related with Wntl3 and ATPase3. PMID: 17649721
    9. findings suggest that a component of 19S regulatory particles directly binds AR and might participate in AR-mediated transcriptional activation in cooperation with TBPIP. PMID: 19325002

    顯示更多

    收起更多

  • 亞細(xì)胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    AAA ATPase family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 9549

    OMIM: 186852

    KEGG: hsa:5702

    STRING: 9606.ENSP00000298852

    UniGene: Hs.250758



主站蜘蛛池模板： 少妇spa推油被扣高潮| 亚洲国产成人精品无码区99| 日本强伦姧人妻一区二区 | 免费精品国偷自产在线在线| 国产内射一区亚洲| 欧美成人a在线网站| 国产成人久久精品一区二区三区 | 日本熟妇人妻中出| 久久婷婷久久一区二区三区| 成人精品免费视频在线观看| 日韩欧美亚洲综合久久影院| 亚洲精品久久无码av片| 亚洲国产成人精品一区刚刚| 国产成熟妇女性视频电影| 国产精品久久久久久人妻精品| 国产精品9999久久久久仙踪林| 97视频精品全国免费观看| 精品精品国产理论在线观看| 国产精品人人做人人爽人人添| 亚洲熟妇久久精品| 日本国产网曝视频在线观看| 伊人久久大香线焦av色| 免费三级网站| 亚洲欧美一区二区三区| 国产成人一区二区无码不卡在线 | 乱码精品一区二区三区| 内射老阿姨1区2区3区4区| 四虎影视成人永久免费观看视频| 国产99在线 | 免费| 亚洲精品无码aⅴ中文字幕蜜桃| 国产小呦泬泬99精品| 中文字幕精品久久久久人妻红杏ⅰ| 超清制服丝袜无码av福利网| 色综合久久久无码中文字幕波多| 色拍拍在线精品视频| 亚洲处破女av日韩精品波波网| 精品国产日韩亚洲一区| 18禁高潮出水呻吟娇喘蜜芽| 国产在线精品99一卡2卡| 亚洲人成小说网站色在线观看| 无码人妻精品一区二区蜜桃色欲 |