在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PSMA7 Antibody

PSMA7 Antibody

  • 中文名稱：
    PSMA7兔多克隆抗體
  • 貨號：
    CSB-PA018873GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PSMA7
  • 別名：
    C6 antibody; HSPC antibody; MGC3755 antibody; OTTHUMP00000031449 antibody; OTTHUMP00000031450 antibody; OTTHUMP00000031453 antibody; Proteasome (prosome macropain) subunit alpha type 7 antibody; Proteasome alpha 7 subunit antibody; Proteasome subunit alpha 4 antibody; Proteasome subunit alpha type 7 antibody; Proteasome subunit alpha type-7 antibody; Proteasome subunit RC6 1 antibody; Proteasome subunit RC6-1 antibody; Proteasome subunit XAPC7 antibody; PSA7_HUMAN antibody; PSMA 7 antibody; PSMA7 antibody; RC6 1 antibody; XAPC7 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PSMA7
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Component of the 20S core proteasome complex involved in the proteolytic degradation of most intracellular proteins. This complex plays numerous essential roles within the cell by associating with different regulatory particles. Associated with two 19S regulatory particles, forms the 26S proteasome and thus participates in the ATP-dependent degradation of ubiquitinated proteins. The 26S proteasome plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins that could impair cellular functions, and by removing proteins whose functions are no longer required. Associated with the PA200 or PA28, the 20S proteasome mediates ubiquitin-independent protein degradation. This type of proteolysis is required in several pathways including spermatogenesis (20S-PA200 complex) or generation of a subset of MHC class I-presented antigenic peptides (20S-PA28 complex). Inhibits the transactivation function of HIF-1A under both normoxic and hypoxia-mimicking conditions. The interaction with EMAP2 increases the proteasome-mediated HIF-1A degradation under the hypoxic conditions. Plays a role in hepatitis C virus internal ribosome entry site-mediated translation. Mediates nuclear translocation of the androgen receptor (AR) and thereby enhances androgen-mediated transactivation. Promotes MAVS degradation and thereby negatively regulates MAVS-mediated innate immune response.
  • 基因功能參考文獻：
    1. salivary exosomal PSMA7 was present at high levels in salivary exosomes from subjects with Inflammatory bowel disease. It can be a very promising biomarker PMID: 28523434
    2. Studies have found significant associations of the treatment response with the 26S proteasome non-ATPase subunit 9 (PSMD9), proteasome alpha type 7 subunit (PSMA7) and PSMD13 genes. PMID: 26624926
    3. c-Abl regulates proteasome abundance by controlling the ubiquitin-proteasomal degradation of PSMA7 subunit PMID: 25620702
    4. PSMA7 functions partially through downregulation NOD1. PMID: 23839082
    5. PSMA7 inhibits the proliferation, tumorigenicity and invasion of A549 cells in vitro PMID: 22584585
    6. High expression of PSMA7 was significantly correlated with liver metastasis. PMID: 19062718
    7. The present study demonstrates that c-Abl and Arg (abl-related gene) tyrosine kinases associate with and phosphorylate the proteasome PSMA7 (alpha4) subunit at Tyr-153. PMID: 16678104
    8. PSMA7 may play an important role in colorectal cancer progression. PMID: 18202793
    9. cell surface binding of EMAP-II results in its internalization into the cytoplasmic compartment where it interacts with PSMA7, a component of the proteasome degradation pathway. This interaction increases HIF-1alpha degradation under hypoxic conditions. PMID: 19362550

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm. Nucleus.
  • 蛋白家族：
    Peptidase T1A family
  • 數據庫鏈接：

    HGNC: 9536

    OMIM: 606607

    KEGG: hsa:5688

    STRING: 9606.ENSP00000359910

    UniGene: Hs.233952



主站蜘蛛池模板： 啪啪后入内射日韩| 1000部啪啪未满十八勿入下载| 亚洲精品无码mⅴ在线观看| 又爽又黄又无遮挡的激情视频免费| 少妇激情作爱视频| 人人爽人人片人人片av| 麻豆 美女 丝袜 人妻 中文| 亚洲精品一品区二品区三区| 亚洲一区精品无码色成人| 亚洲人成色77777| 免费无码不卡视频在线观看| 小12萝裸体视频国产| 99国产揄拍国产精品人妻| 午夜成人鲁丝片午夜精品 | 五月婷婷久久草| 插b内射18免费视频| 色欲人妻aaaaaaa无码| 国产午夜精品一区二区三区老| 国内精品久久久久久久电影视 | 成人精品一区二区三区电影| 秋霞国产成人精品午夜视频app | 亚洲精品久久久久一区二区三区 | 国产亚洲久久久久久久| 久久精品国产99精品国产2021| 色情无码一区二区三区| 伊伊人成亚洲综合人网| 久久国产乱子伦免费精品| 国产超碰人人爽人人做| 波多野结衣乱码中文字幕| 日韩一区二区三区四区区区| 强奷乱码中文字幕熟女一| 欧美成人看片一区二区| 久久99日韩国产精品久久99| 精品卡一卡二卡3卡高清乱码| 日韩精品区一区二区三vr| 成人av在线一区二区三区| 亚洲一卡2卡3卡4卡精品 | 亚洲精品成人av在线| а天堂中文地址在线| 欧美日韩精品suv| 免费无码又爽又刺激高潮的app|