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  4. PSD4 Antibody, HRP conjugated

PSD4 Antibody, HRP conjugated

  • 中文名稱：
    PSD4兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA843332LB01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PSD4 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    EFA6B antibody; Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6B antibody; FLJ36237 antibody; FLJ37279 antibody; PH and SEC7 domain-containing protein 4 antibody; Pleckstrin homology and SEC7 domain-containing protein 4 antibody; Ppleckstrin and Sec7 domain containing 4 antibody; PSD4 antibody; PSD4_HUMAN antibody; SEC7 homolog antibody | telomeric of interleukin-1 cluster protein antibody; Telomeric of interleukin-1 cluster protein antibody; TIC antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human PH and SEC7 domain-containing protein 4 protein (1-300AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Guanine nucleotide exchange factor for ARF6 and ARL14/ARF7. Through ARL14 activation, controls the movement of MHC class II-containing vesicles along the actin cytoskeleton in dendritic cells. Involved in membrane recycling. Interacts with several phosphatidylinositol phosphate species, including phosphatidylinositol 3,4-bisphosphate, phosphatidylinositol 3,5-bisphosphate and phosphatidylinositol 4,5-bisphosphate.
  • 基因功能參考文獻：
    1. results identify EFA6B as a novel antagonist in breast cancer and they point to its regulatory and signaling pathways as rational therapeutic targets in aggressive forms of this disease PMID: 25115298
    2. One of the cytohesin family of guanine nucleotide exchange factors, Tic may act on the ARF family of GTP-binding proteins. A PH domain with similar sequence and relative position to those in other cytohesins may allow association with phosphoinositides. PMID: 11050434
  • 亞細胞定位：
    Cell membrane. Cell projection, ruffle membrane.
  • 組織特異性：
    Widely expressed. Highest levels of expression are found in placenta, pancreas, spleen, thymus and peripheral blood.
  • 數據庫鏈接：

    HGNC: 19096

    OMIM: 614442

    KEGG: hsa:23550

    STRING: 9606.ENSP00000245796

    UniGene: Hs.516306



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