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  4. PRTFDC1 Antibody

PRTFDC1 Antibody

  • 中文名稱：
    PRTFDC1兔多克隆抗體
  • 貨號：
    CSB-PA018827GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PRTFDC1
  • 別名：
    FLJ11888 antibody; HHGP antibody; OTTHUMP00000019332 antibody; Phosphoribosyl transferase domain containing 1 antibody; phosphoribosyltransferase domain containing protein 1 antibody; Phosphoribosyltransferase domain-containing protein 1 antibody; PRDC1_HUMAN antibody; prtfdc1 antibody; Uncharacterized protein PRTFDC1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Human PRTFDC1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
  • 基因功能參考文獻：
    1. We found evidence for PRTFDC1 as a potential novel PTSD gene, a finding that awaits further replication. PMID: 25456346
    2. These results demonstrate that PRTFDC1 is a genetic modifier of HPRT-deficiency in the mouse. PMID: 21818316
    3. The PRTFDC1 structure has been determined at 1.7 A resolution with bound GMP. The overall structure and GMP binding mode are very similar to that observed for HPRT. PMID: 21054786
    4. epigenetic silencing of PRTFDC1 by hypermethylation of the CpG island leads to a loss of PRTFDC1 function, which might be involved in squamous cell oral carcinogenesis. PMID: 17599052
  • 蛋白家族：
    Purine/pyrimidine phosphoribosyltransferase family
  • 數據庫鏈接：

    HGNC: 23333

    OMIM: 610751

    KEGG: hsa:56952

    STRING: 9606.ENSP00000318602

    UniGene: Hs.405619



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