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PRSS56 Antibody, FITC conjugated

  • 中文名稱:
    PRSS56兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA317372LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PRSS56 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PRSS56
  • 別名:
    PRSS56 antibody; Serine protease 56 antibody; EC 3.4.21.- antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Serine protease 56 protein (36-116AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Serine protease required during eye development.
  • 基因功能參考文獻:
    1. variations in PRSS56 were evaluated in patients with either primary angle-closure glaucoma (PACG) or high hyperopia. PMID: 24227917
    2. Idenification of a founder mutation in the PRSS56 gene in Tunisian families with posterior microphthalmia and nanophthalmia. PMID: 23820083
    3. Corneal diameter decreases with decreasing axial length, suggesting posterior microphthalmos and nanophthalmos represent a spectrum of high hyperopia rather than distinct phenotypes. In the Saudi population PRSS56 mutations are the major cause. PMID: 23127749
    4. PRSS56 is a good candidate for the causal gene for nanophthalmos in a Mexican-Canadian family cohort. PMID: 21850159
    5. Together, these data suggest that alterations of this serine protease may contribute to a spectrum of human ocular conditions including reduced ocular size and ACG. PMID: 21532570
    6. Three different mutations in PRSS56, were detected in microphthalmos patients of the Faroese families. PMID: 21397065

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  • 相關疾病:
    Microphthalmia, isolated, 6 (MCOP6)
  • 蛋白家族:
    Peptidase S1 family
  • 組織特異性:
    Expressed neural retina, cornea, sclera and optic nerve.
  • 數據庫鏈接:

    HGNC: 39433

    OMIM: 613517

    KEGG: hsa:646960

    UniGene: Hs.570310



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