在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PRRX1 Antibody

  • 中文名稱:
    PRRX1兔多克隆抗體
  • 貨號:
    CSB-PA003862
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Jurkat cells using PRX1 Polyclonal Antibody
    • Western Blot analysis of Jurkat cells using PRX1 Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    PRRX1
  • 別名:
    AGOTC antibody; Homeobox protein PHOX1 antibody; Paired mesoderm homeo box 1 antibody; Paired mesoderm homeobox 1 antibody; paired mesoderm homeobox 1 isoform pmx-1b antibody; Paired mesoderm homeobox protein 1 antibody; Paired related homeobox 1 antibody; Paired related homeobox protein 1 antibody; Paired-related homeobox protein 1 antibody; PHOX 1 antibody; PHOX1 1, 2 antibody; PHOX1 antibody; PMX 1 antibody; PMX1 antibody; PRRX 1 antibody; Prrx1 antibody; PRRX1_HUMAN antibody; PRX 1 antibody; PRX-1 antibody; PRX1 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PRX1.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:10000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein binds to an A/T-rich element in the muscle creatine enhancer.
  • 基因功能參考文獻:
    1. Low PRRX1 expression is associated with hepatocellular carcinoma. PMID: 28677793
    2. identified a functional genetic variant that alters PRRX1 expression, ultimately resulting in electrophysiological alterations in atrial myocytes that may promote Atrial fibrillation. PMID: 28974514
    3. The glioma-initiating cells self-renewal function regulated by PRRX1 is mediated by dopamine D2 receptor (DRD2). PRRX1 directly binds to the DRD2 promoter and transactivates its expression in glioma-initiating cells. PMID: 28486630
    4. LGR5-expressing fraction of CD54+ cells represents gastric cancer CSCs, in which LGR5 is closely associated with stemness and EMT core genes PMID: 28033430
    5. Prrx1b may be an important regulator of epithelial-mesenchymal transition in Triple-negative breast cancer cells. PMID: 27027510
    6. miR-655 inhibits the acquisition of the epithelial-mesenchymal transition phenotype in triple-negative breast cancer by down-regulating Prrx1, thereby inhibiting cell migration and invasion during cancer progression. PMID: 26820102
    7. Decreased Expression of PRRX1 was Associated with Hepatocellular Carcinoma. PMID: 25404478
    8. the switch from Prrx1b to Prrx1a governs EMT plasticity in both mouse models of PDAC and human PDAC PMID: 26773005
    9. These findings demonstrate that PRRX1 promotes epithelial-mesenchymal transition in gastric cancer cells PMID: 25428393
    10. Our results indicate that activation of Notch signaling by PRRX1 is associated with the promotion of glioblastoma cell invasion. PMID: 25522823
    11. We conclude that miR-146b-5p has a role in cell proliferation and invasion, and that PRRX1 plays an important role in papillary thyroid carcinoma epithelial-mesenchymal transition and disease progression. PMID: 24946010
    12. Overexpression of PRRX1 in stably overexpressed-miR-124 cell lines could rescue the effects of radiosensitivity enhancement brought by miR-124. PMID: 24705396
    13. In the rare variant joint analysis, damaging variants within the PRRX1 region showed significant association with AF. PMID: 24239840
    14. PRRX1 is an indicator of metastasis and poor prognosis in colorectal cancer cases. PMID: 23807160
    15. The homeobox factor Prrx1 is an EMT inducer conferring migratory and invasive properties. PMID: 23201163
    16. We show that the homeobox factor Prrx1 is an EMT inducer conferring migratory and invasive properties. The loss of Prrx1 is required for cancer cells to metastasize in vivo, which revert to the epithelial phenotype concomitant with the acquisition of stem cell properties. PMID: 23201163
    17. Mutation analysis was performed after sequencing the entire coding regions of OTX2 and PRRX1 genes isolated from the proband and his parents. After thorough analysis, no DNA variations were detected. PMID: 22198066
    18. identification of the two Prx1 target genes, which play a pivotal role in development of liver fibrosis, is a novel finding for liver pathophysiology PMID: 18296734

    顯示更多

    收起更多

  • 相關疾病:
    Agnathia-otocephaly complex (AGOTC)
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    Paired homeobox family
  • 數據庫鏈接:

    HGNC: 9142

    OMIM: 167420

    KEGG: hsa:5396

    STRING: 9606.ENSP00000239461

    UniGene: Hs.283416



主站蜘蛛池模板: 337p西西人体大胆瓣开下部| 无码人妻av免费一区二区三区| 亚洲色婷婷一区二区三区| 亚洲精品久久国产高清情趣图文| 动漫av永久无码精品每日更新| 99在线精品视频高潮喷吹| 欧美日韩在线视频一区| 阳茎伸入女人阳道视频免费| 饥渴少妇av无码影片| 国内精品久久久久久久电影视| 日日碰狠狠添天天爽无码| 亚洲午夜无码久久久久| 18禁真人抽搐一进一出在线| 成人av一本不卡二卡| yy111111少妇无码影院| 最近免费中文字幕大全免费版视频| 欧美成 人影片 aⅴ免费观看| 噜噜久久噜噜久久鬼88| 99久久精品无码一区二区三区| 一群黑人大战亚裔女在线播放| 动漫av纯肉无码免费播放| 激情内射亚洲一区二区三区| 人妻奶水人妻系列| 成视频年人黄网站视频福利| 国产精品自在拍首页视频| 乱人伦人妻中文字幕无码| 四虎亚洲欧美成人网站| 国产成人片无码免费视频软件| 午夜成人无码福利免费视频| 国产97色在线 | 免费| 欧美成人a天堂片在线观看| 西西人体做爰大胆性自慰 | 欧美老熟妇videos极品另类| 麻豆国产精品va在线观看| 久久―日本道色综合久久| 欧美日韩精品| 欧美成人一区二免费视频| 玩弄丰满奶水的女邻居| 秋霞av鲁丝片一区二区| 亚洲人成色4444在线观看| 野花在线无码视频在线播放|