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  4. PRPF18 Antibody

PRPF18 Antibody

  • 中文名稱：
    PRPF18兔多克隆抗體
  • 貨號(hào)：
    CSB-PA130292
  • 規(guī)格：
    ￥2024
  • 圖片：
    • Western blot analysis of extracts from HuvEc cells, MCF-7 cells and 293 cells, using PRPF18 antibody.
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PRPF18 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PRPF18
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse
  • 免疫原：
    Synthesized peptide derived from internal of Human PRPF18.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 克隆類型：
    Polyclonal
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:3000
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Participates in the second step of pre-mRNA splicing.
  • 基因功能參考文獻(xiàn)：
    1. These results validated the association of two previously known skin pigmentation genes, SLC24A5 (minimum p = 2.62 x 10(-14), rs1426654) and SLC45A2 (minimum p = 9.71 x 10(-10), rs16891982), and revealed the intergenic region of BEND7 and PRPF18 as a novel locus associated with this trait (minimum p = 4.58 x 10(-9), rs6602666). PMID: 28300201
    2. We identified the pre-mRNA processing factor Prp18 as a stimulatory factor for influenza virus RNA synthesis. Prp18 facilitates the elongation reaction of viral polymerases by preventing the deleterious annealing of newly synthesized RNA to the template. Prp18 functions as a chaperone for NP to stimulate the formation of NP-RNA complexes. PMID: 27852861
    3. Presented is solution structure of the splicing factor motif of hPrp18, which forms a compact fold with two a helices interacting head-to-tail and a fixed linker loop. PMID: 22213562
  • 亞細(xì)胞定位：
    Nucleus speckle.
  • 蛋白家族：
    PRP18 family
  • 數(shù)據(jù)庫(kù)鏈接：

    HGNC: 17351

    OMIM: 604993

    KEGG: hsa:8559

    STRING: 9606.ENSP00000367835

    UniGene: Hs.660649



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