在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PRKX Antibody

PRKX Antibody

  • 中文名稱：
    PRKX兔多克隆抗體
  • 貨號：
    CSB-PA051875
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA051875(PRKX Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA051875(PRKX Antibody) at dilution 1/20, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A549 cells, Jurkat cells, 293T cells, K562 cells, Primary antibody: CSB-PA051875(PRKX Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PRKX
  • 別名：
    PKX1 antibody; PRKX antibody; PRKX_HUMAN antibody; Protein kinase PKX1 antibody; Serine/threonine-protein kinase PRKX antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthetic peptide of Human PRKX
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:1000-1:2000
    WB 1:200-1:1000
    IHC 1:15-1:50
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation.
  • 基因功能參考文獻：
    1. PRKX, WNT3 and WNT16 genes, belonging to the WNT signaling pathway, are involved in the tumorigenic process of nodular basal cell carcinoma PMID: 27630294
    2. The characteristics and developmental functions of PRKX. [review] PMID: 26252946
    3. findings reveals a major role of PRKX, TTBK2 and RSK4 in triggering Sunitinib resistance formation; data suggest transcriptional regulation of these kinases together with other proteins might play an important role in formation of Sunitinib resistance by affecting transcription factors PMID: 22020623
    4. MBD 4--a potential substrate for protein kinase X PMID: 21971312
    5. The interaction of PRKX with Pin-1, Magi-1 and Bag-3 could contribute to the stimulating role of PRKX in angiogenesis. PMID: 21684272
    6. PRKX kinase may regulate epithelial morphogenesis during mammalian kidney development. PMID: 12082174
    7. PRKX can restore normal function to PKD1-deficient kidneys and have implications for the development of preventative therapy for autosomal dominant polycystic kidney disease PMID: 17980165

    顯示更多

    收起更多

  • 相關疾病：
    A chromosomal aberration involving PRKX is a cause of sex reversal disorder. Translocation t(X;Y)(p22;p11) with PRKY. Chromosomal translocations proximal to PRKY account for about 30% of the cases of sex reversal disorder in XX males and XY females.
  • 亞細胞定位：
    Cytoplasm. Nucleus. Note=cAMP induces nuclear translocation.
  • 蛋白家族：
    Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily
  • 組織特異性：
    Widely expressed (at protein level). Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982.
  • 數據庫鏈接：

    HGNC: 9441

    OMIM: 300083

    KEGG: hsa:5613

    STRING: 9606.ENSP00000262848

    UniGene: Hs.390788



主站蜘蛛池模板： 亚洲精品久久午夜无码一区二区 | 久久青青草原国产最新片完整| 粗大的内捧猛烈进出看视频| 亚洲日韩欧美一区二区三区| 国产免费无遮挡吸乳视频| 欧美老熟妇喷水| 日产精品卡1卡2卡三卡在线| 伊人久久精品无码麻豆一区| 99热这里只有精品免费播放| 成av人电影在线观看| 中文字幕无码专区人妻系列| 漂亮人妻被强中文字幕久久| 超碰国产精品久久国产精品99 | 色婷婷综合中文久久一本| 色狠狠一区二区三区香蕉| 97性无码区免费| 久久久久久人妻精品一区| 爱做久久久久久| 99久久国语露脸精品国产色| 国产成人片无码免费视频软件| 人妻丰满熟妇av无码区app| 伊人激情av一区二区三区 | 野外亲子乱子伦视频丶| 无码精品人妻一区二区三区免费看 | 国产精品18久久久久久vr | 中文字幕av无码专区第一页| 无码国产伦一区二区三区视频| 乱码人妻一区二区三区| 亚洲日韩a∨无码久| 国产精品无码午夜福利| 国产美女在线精品免费观看| 亚 洲 成 人 网站在线观看| 无码专区—va亚洲v专区| 天躁夜夜躁狼狠躁| 亚洲精品国产精品制服丝袜| 高中国产开嫩苞实拍视频在线观看| 麻豆一区二区在我观看| 国产乱子经典视频在线观看| 人人玩人人添人人澡欧美| 久爱www成人网免费视频| 性大毛片视频|