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  4. PRKAR1B Antibody

PRKAR1B Antibody

  • 中文名稱：
    PRKAR1B兔多克隆抗體
  • 貨號：
    CSB-PA003797
  • 規格：
    ￥1090
  • 圖片：
    • Western Blot analysis of COLO205 cells using PKA Iβ reg Polyclonal Antibody
    • Western Blot analysis of K562 cells using PKA Iβ reg Polyclonal Antibody
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    cAMP dependent protein kinase type I beta regulatory subunit antibody; cAMP-dependent protein kinase type I-beta regulatory subunit antibody; KAP1_HUMAN antibody; PKARI beta antibody; PRKAR 1 antibody; PRKAR 1B antibody; PRKAR1 antibody; Prkar1b antibody; PRKAR1B protein antibody; Protein kinase cAMP dependent regulatory type I beta antibody; RIbeta antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PKA Iβ reg.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells.
  • 基因功能參考文獻：
    1. No pathogenic PRKAR1B mutations were found in early onset familial dementia patients in a Dutch cohort. PMID: 25108559
    2. This study demonistrated that PRKAR1B mutation associated with a new neurodegenerative disorder with unique pathology. PMID: 24722252
    3. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID: 11943777
  • 亞細胞定位：
    Cell membrane.
  • 蛋白家族：
    CAMP-dependent kinase regulatory chain family
  • 組織特異性：
    Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible.
  • 數據庫鏈接：

    HGNC: 9390

    OMIM: 176911

    KEGG: hsa:5575

    STRING: 9606.ENSP00000353415

    UniGene: Hs.520851



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