在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PRCP Antibody

PRCP Antibody

  • 中文名稱：
    PRCP兔多克隆抗體
  • 貨號：
    CSB-PA018636LA01HU
  • 規格：
    ￥440
  • 圖片：
    • Immunofluorescence staining of Hela cells with CSB-PA018636LA01HU at 1:166, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PRCP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Angiotensinase C antibody; HUMPCP antibody; Lysosomal carboxypeptidase C antibody; Lysosomal Pro X carboxypeptidase antibody; Lysosomal Pro-X carboxypeptidase antibody; MGC2202 antibody; PCP antibody; PCP_HUMAN antibody; PRCP antibody; Proline carboxypeptidase antibody; Prolylcarboxypeptidase (angiotensinase C) antibody; Prolylcarboxypeptidase antibody; prolylcarboxypeptidase isoform 1 preproprotein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Lysosomal Pro-X carboxypeptidase protein (347-443AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PRCP Antibody (CSB-PA018636LA01HU)，的標記方式是Non-conjugated。對于PRCP Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA018636LB01HU PRCP Antibody, HRP conjugated ELISA
    FITC CSB-PA018636LC01HU PRCP Antibody, FITC conjugated
    Biotin CSB-PA018636LD01HU PRCP Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IF
  • 推薦稀釋比：
    Application Recommended Dilution
    IF 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cleaves C-terminal amino acids linked to proline in peptides such as angiotensin II, III and des-Arg9-bradykinin. This cleavage occurs at acidic pH, but enzymatic activity is retained with some substrates at neutral pH.
  • 基因功能參考文獻：
    1. For the first time, PRCP is identified as an apelin-cleaving enzyme. PMID: 27449720
    2. The decrease in PRCP levels in the first 24 h after stroke onset is associated with stroke severity and an unfavourable short-term stroke outcome PMID: 25370794
    3. PRCP1 interacts with plasma kallikrein (PK) at multiple sites for PK activation. PMID: 25324000
    4. The present results indicated PRCP rs7104980 can be considered as a marker for EH and Hap3 GAGCACTAACA (PRCP) and Hap16 TTTA (CMA1) might be associated with essential hypertension in Chinese Han population. PMID: 22679278
    5. PRCP regulates cell growth, angiogenesis, and the response to vascular injury PMID: 23744584
    6. analysis of non-benzimidazole and brain-penetrant prolylcarboxypeptidase inhibitors PMID: 22079761
    7. PRCP as a resistance factor for 4OHTAM resistance in estrogen receptor-positive breast cancer cells. PMID: 21087932
    8. A single peptide, with the sequence YPRPIHPA, as a novel substrate for PRCP in human cerebrospinal fluid. PMID: 20517885
    9. Purified PrCP yielded crystals belonging to space group R32, with unit-cell parameters a = b = 181.14, c = 240.13 A, that diffracted to better than 2.8 A resolution. PMID: 20516604
    10. A structure-based alignment with the previously undescribed structure of DPP7 illuminates the mechanism of orthogonal substrate specificity of PRCP and DPP7. PMID: 20540760
    11. Data suggest that the E112D polymorphism in the PRCP gene may be a useful genetic marker to predict the antihypertensive effect of short-term benazepril treatment in hypertensive patients. PMID: 20079160
    12. PRCP appears to be a HUVEC-associated prekallikrein activator. PMID: 11830581
    13. Identification of prolylcarboxypeptidase as the cell matrix-associated prekallikrein activator. PMID: 12123826
    14. recombinant protein, identical to enzyme from human umbilical vein endothelial cells, is a prekallikrein activator. PMID: 14996700
    15. Prolylcarboxypepdiase E112D (rs2298668)D allele alone and jointly with chronic hypertension were associated with a significantly increased risk of preeclampsia PMID: 16681991
    16. role in regulation cardiovascular tone; proinflammatory agent PMID: 18396440
    17. These investigations showed that the C-terminal region of the rPRCP(40) contributes to PRCP's catalytic function, and provided additional experimental evidence for this suggestion. PMID: 18656443

    顯示更多

    收起更多

  • 亞細胞定位：
    Lysosome.
  • 蛋白家族：
    Peptidase S28 family
  • 組織特異性：
    Highest levels in placenta, lung and liver. Also present in heart, brain, pancreas and kidney.
  • 數據庫鏈接：

    HGNC: 9344

    OMIM: 176785

    KEGG: hsa:5547

    STRING: 9606.ENSP00000377055

    UniGene: Hs.523936



主站蜘蛛池模板： 98久久人妻少妇激情啪啪| 又黄又爽又无遮挡免费的网站| 国产精品igao视频网| 欧美色欧美亚洲日韩在线播放| 多人伦交性欧美| 亚洲精品一线二线三线无人区| 夜夜夜高潮夜夜爽夜夜爰爰| 欧美黑人巨大videos精品男男| av性色在线乱叫| 水蜜桃色314在线观看| 国产suv精品一区二区6| 欧美亚洲另类 丝袜综合网| 成 人 网 站 免费 在线| 一本一道久久综合狠狠老| 亚欧无线一线二线三线区别| 怀孕挺大肚子疯狂高潮av毛片| 国产日产欧美最新| 曰曰摸夜夜添夜夜添高潮出水| 欧美又大又粗午夜剧场免费| 无码av中文一区二区三区 | 九九视频免费精品视频| 亚洲欧洲日产国码无码av一| 成人爱做日本视频免费| 国产高清视频在线观看97| 亚洲人ⅴsaⅴ国产精品| 国产香蕉视频在线播放| 丰满日韩放荡少妇无码视频| 他掀开裙子把舌头伸进去添视频| 成人综合婷婷国产精品久久蜜臀 | 日韩中文高清在线专区| 亚洲最大无码av网站观看| 国产热re99久久6国产精品首页| 国产亚洲日韩欧美一区二区三区| 色www永久免费视频首页| 久久好在线视频| 国产精品一品二区三区的使用体验| 国产精品卡1卡2卡三卡四| 国产成人综合一区人人| 国模冰莲自慰肥美胞极品人体图| 国产成人综合欧美精品久久| 日韩欧美tⅴ一中文字暮|