在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PRA1 Antibody

PRA1 Antibody

Rare Species
  • 中文名稱：
    PRA1兔多克隆抗體
  • 貨號：
    CSB-PA308545YA01CZD
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: PRA1 antibody at 4.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 55 kDa
      Observed band size: 55 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Candida albicans PRA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PRA1
  • 別名：
    PRA1 antibody; FBP1 antibody; CAALFM_C406980WA antibody; CaO19.10623 antibody; CaO19.3111 antibody; pH-regulated antigen PRA1 antibody; 58 kDa fibrinogen-binding mannoprotein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Candida albicans
  • 免疫原：
    Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA)
  • 免疫原種屬：
    Candida albicans
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PRA1 Antibody (CSB-PA308545YA01CZD)，的標記方式是Non-conjugated。對于PRA1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA308545YB01CZD PRA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA308545YC01CZD PRA1 Antibody, FITC conjugated
    Biotin CSB-PA308545YD01CZD PRA1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages.
  • 基因功能參考文獻：
    1. Pra1 is a hierarchical complement inhibitor that targets C3 by cleaving C3 at a unique site. This inhibited effector function of the activation fragments. Pra1 also bound to C3a and C3b generated by human convertases and blocked their effector functions, C3a binding to human C3a receptor, calcium signaling, IL-8 release, C3b deposition, opsonophagocytosis, and killing by neutrophils. PMID: 28860090
    2. surface-exposed Pra1 plays a role in the recognition of Candida albicans, especially hyphal cells, by human neutrophils PMID: 21820180
    3. recognition of pH-regulated antigen 1 protein (Pra1p) by integrin alpha(M)betaplays a pivotal role in determining fungal virulence and host response and protection against C. albicans infection PMID: 21245270
    4. Data show that the fungus secretes a potent complement inhibitor, pH-regulated Ag 1 (Pra1), which in the direct surrounding of the pathogen binds to fluid-phase C3 and blocks cleavage of C3 to C3a and C3b. PMID: 20644161
    5. Therefore, it appears that Pra1p can play at most a minor role in fibrinogen binding to C. albicans. PMID: 18625733
    6. The pH-regulated antigen 1 (Pra1) protein was identified as a novel Factor H and FHL-1 binding protein. PMID: 19850343

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Note=Found primarily on the cell surface of filamentous forms and enriched at hyphal tips.
  • 蛋白家族：
    ZPS1 family
  • 數據庫鏈接：


主站蜘蛛池模板： 无码av中文字幕免费放 | 国产成人无码一区二区三区在线| 亚洲中文字幕久久无码| 久久伊人五月丁香狠狠色| 暖暖 免费 高清 日本 在线| 亚洲色欲色欲天天天www| 男女一边摸一边做爽爽的免费阅读| 99热在线精品国产观看| 伊人久久大香线蕉综合75| 熟女体下毛毛黑森林| 无码专区 丝袜美腿 制服师生| 人人人插人人费| 巨大乳女人做爰视频在线看| 又黄又爽的60分钟视频| 老妇女性较大毛片| 欧美人与禽zoz0性伦交| 亚洲欧美日韩视频高清专区| 亚洲综合成人av一区在线观看| 无码一区二区三区在线| 精品欧美乱码久久久久久1区2区| 中文字幕无码日韩欧免费软件| 欧美性猛交xxxxx按摩欧美 | 老司机午夜福利视频| 国产精品99久久免费| 在线观看国产精品乱码app| 华人少妇被黑人粗大的猛烈进| 国产精品日本一区二区在线播放| 久久超碰色中文字幕超清| 国产欧美丝袜在线二区| 久久精品国产69国产精品亚洲| 国产精品欧美一区二区三区 | 黑人巨大跨种族video| 爽爽午夜影视窝窝看片| 国产裸体歌舞一区二区| 久久精品国产69国产精品亚洲| 99精品国产99久久久久久97| 人人澡人人曰人人摸看| 久久无码人妻一区二区三区午夜 | 欧美18精品久久久无码午夜福利| 2021最新国产精品网站| 久久偷看各类wc女厕嘘嘘偷窃|