在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PRA1 Antibody

PRA1 Antibody

Rare Species
  • 中文名稱：
    PRA1兔多克隆抗體
  • 貨號：
    CSB-PA308545YA01CZD
  • 規格：
    ￥440
  • 圖片：
    • Western Blot
      Positive WB detected in Recombinant protein
      All lanes: PRA1 antibody at 4.7μg/ml
      Secondary
      Goat polyclonal to rabbit IgG at 1/50000 dilution
      Predicted band size: 55 kDa
      Observed band size: 55 kDa
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Candida albicans PRA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PRA1
  • 別名：
    PRA1 antibody; FBP1 antibody; CAALFM_C406980WA antibody; CaO19.10623 antibody; CaO19.3111 antibody; pH-regulated antigen PRA1 antibody; 58 kDa fibrinogen-binding mannoprotein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Candida albicans
  • 免疫原：
    Recombinant Candida albicans pH-regulated antigen PRA1 protein (16-299AA)
  • 免疫原種屬：
    Candida albicans
  • 標記方式：
    Non-conjugated

    本頁面中的產品，PRA1 Antibody (CSB-PA308545YA01CZD)，的標記方式是Non-conjugated。對于PRA1 Antibody，我們還提供其他標記。見下表：

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA308545YB01CZD PRA1 Antibody, HRP conjugated ELISA
    FITC CSB-PA308545YC01CZD PRA1 Antibody, FITC conjugated
    Biotin CSB-PA308545YD01CZD PRA1 Antibody, Biotin conjugated ELISA
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:5000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Cell surface protein involved in the host-parasite interaction during candidal infection. With MP65, represents a major component of the biofilm matrix. Sequesters zinc from host tissue and mediates leukocyte adhesion and migration. As a surface protein, binds the two human complement regulators CFH and CFHR1, as well as plasminogen PLG, mediates complement evasion and extra-cellular matrix interaction and/or degradation. As a released protein, enhances complement control in direct vicinity of the yeast and thus generates an additional protective layer which controls host complement attack, assisting the fungus in escaping host surveillance. Binds to host fluid-phase C3 and blocks cleavage of C3 to C3a and C3b, leading to inhibition of complement activation. Mediates also human complement control and complement evasion through binding to C4BPA, another human complement inhibitor, as well as through binding to host integrin alpha-M/beta-2. Decreases complement-mediated adhesion, as well as uptake of C.albicans by human macrophages.
  • 基因功能參考文獻：
    1. Pra1 is a hierarchical complement inhibitor that targets C3 by cleaving C3 at a unique site. This inhibited effector function of the activation fragments. Pra1 also bound to C3a and C3b generated by human convertases and blocked their effector functions, C3a binding to human C3a receptor, calcium signaling, IL-8 release, C3b deposition, opsonophagocytosis, and killing by neutrophils. PMID: 28860090
    2. surface-exposed Pra1 plays a role in the recognition of Candida albicans, especially hyphal cells, by human neutrophils PMID: 21820180
    3. recognition of pH-regulated antigen 1 protein (Pra1p) by integrin alpha(M)betaplays a pivotal role in determining fungal virulence and host response and protection against C. albicans infection PMID: 21245270
    4. Data show that the fungus secretes a potent complement inhibitor, pH-regulated Ag 1 (Pra1), which in the direct surrounding of the pathogen binds to fluid-phase C3 and blocks cleavage of C3 to C3a and C3b. PMID: 20644161
    5. Therefore, it appears that Pra1p can play at most a minor role in fibrinogen binding to C. albicans. PMID: 18625733
    6. The pH-regulated antigen 1 (Pra1) protein was identified as a novel Factor H and FHL-1 binding protein. PMID: 19850343

    顯示更多

    收起更多

  • 亞細胞定位：
    Secreted. Note=Found primarily on the cell surface of filamentous forms and enriched at hyphal tips.
  • 蛋白家族：
    ZPS1 family
  • 數據庫鏈接：


主站蜘蛛池模板： 中文字幕无码日韩欧免费软件 | 国产成人片无码免费视频| 成人片无码免费播放| 不卡av中文字幕手机看 | 欧美日本国产va高清cabal | 国产精品一区二区av麻豆| 欧美性色大片在线观看| 992tv精品视频tv在线观看| 免费网站内射红桃视频| 国产精品偷伦视频免费观看了| 国产欧美日韩综合精品一区二区| 正在播放老肥熟妇露脸| 久久se精品一区精品二区| 国产在线午夜不卡精品影院| 国产精品乱码久久久久软件| 色综合天天综合网国产成人网| 四川丰满少妇被弄到高潮| 国产一区二区不卡老阿姨| 思思99re6国产在线播放| 一本无码中文字幕在线观| 午夜福利伦伦电影理论片在线观看 | 国产午夜精品一区二区三区不卡| 欧美日本国产va高清cabal| 暖暖 免费 高清 日本 在线| 国产丝袜肉丝视频在线| 久久国产亚洲精品无码| 亚洲国产果冻传媒av在线观看 | 寂寞骚妇被后入式爆草抓爆| 亚洲曰本av在线天堂| 老子影院午夜伦不卡无码| 色噜噜av亚洲色一区二区| 一本久久综合亚洲鲁鲁五月天 | 精品久久人妻av中文字幕| 亚洲日韩av无码一区二区三区| 青草影院内射中出高潮-百度| 亚洲乱色伦图片区小说| 天干夜天天夜天干天2004年| 无码精品人妻一区二区三区影院| 亚洲欧美一区二区三区日产| 亚洲精品久久久久久久观小说| 亚洲成a人v电影在线观看|