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  4. PPP2R3C Antibody

PPP2R3C Antibody

  • 中文名稱：
    PPP2R3C兔多克隆抗體
  • 貨號：
    CSB-PA836171ESR2HU
  • 規格：
    ￥440
  • 圖片：
    • Western blot
      All lanes: PPP2R3C antibody at 3.76µg/ml
      Lane 1: Mouse stomach tissue
      Lane 2: A431 whole cell lysate
      Lane 3: Jurkat whole cell lysate
      Lane 4: A549 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 54, 40 kDa
      Observed band size: 54 kDa
    • Immunohistochemistry of paraffin-embedded human brain tissue using CSB-PA836171ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human gastric cancer using CSB-PA836171ESR2HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PPP2R3C Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    C14orf10 antibody; Chromosome 14 open reading frame 10 antibody; G4-1 antibody; G5pr antibody; Hypothetical protein FLJ20644 antibody; P2R3C_HUMAN antibody; ppp2r3c antibody; protein phosphatase 2 (formerly 2A), regulatory subunit B'', gamma antibody; Protein phosphatase 2 regulatory subunit B''gamma antibody; protein phosphatase 2, regulatory subunit B'', gamma antibody; Protein phosphatase subunit G5PR antibody; rhabdomyosarcoma antigen MU-RMS-40.6A antibody; Rhabdomyosarcoma antigen MU-RMS-40.6A/6C antibody; rhabdomyosarcoma antigen Mu-RMS-40.6C antibody; serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human, Mouse
  • 免疫原：
    Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B\'\' subunit gamma protein (1-160AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, WB, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    May regulate MCM3AP phosphorylation through phosphatase recruitment. May act as a negative regulator of ABCB1 expression and function through the dephosphorylation of ABCB1 by TFPI2/PPP2R3C complex. May play a role in the activation-induced cell death of B-cells.
  • 基因功能參考文獻：
    1. Knockdown of PP5 and/or PPP2R3C increased P-gp expression and lowered the sensitivity to vincristine and doxorubicin. Consequently, results indicate that PP5/PPP2R3C negatively regulates P-gp expression and function. PMID: 24333728
    2. G5PR expression is markedly augmented in the centrocytes of germinal centers after immunization of transgenic mice with T cell-dependent antigen. PMID: 22753944
  • 亞細胞定位：
    Nucleus. Cytoplasm.
  • 組織特異性：
    Ubiquitously expressed in brain and other tissues.
  • 數據庫鏈接：

    HGNC: 17485

    OMIM: 615902

    KEGG: hsa:55012

    STRING: 9606.ENSP00000261475

    UniGene: Hs.530712



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