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  4. PPP2R3A Antibody, HRP conjugated

PPP2R3A Antibody, HRP conjugated

  • 中文名稱：
    PPP2R3A兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA21129B0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PPP2R3A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    AI118493 antibody; DNA for thyroid hormone receptor binding site (258bp) antibody; P2R3A_HUMAN antibody; PP2A subunit B B''-PR72/PR130 antibody; PP2A subunit B B72/B130 isoforms antibody; PP2A subunit B isoform PR72/PR130 antibody; PP2A subunit B isoform R3 isoform antibody; PP2A subunit B isoforms B''-PR72/PR130 antibody; PP2A subunit B isoforms B72/B130 antibody; PP2A subunit B PR72/PR130 isoforms antibody; PP2A subunit B R3 isoform antibody; PPP2R3 antibody; Ppp2r3a antibody; PR130 antibody; PR59 antibody; PR72 antibody; Protein phosphatase 2 (formerly 2A) regulatory subunit B'' alpha antibody; Serine/threonine protein phosphatase 2A 72/130 kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B antibody; Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit alpha protein (256-508AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.
  • 基因功能參考文獻：
    1. HDAC1 and HDAC2 suppress the expression of PPP2R3A/PR130, a regulatory subunit of the trimeric serine/threonine phosphatase 2 (PP2A). PMID: 29472538
    2. this study shows the importance of PP2A complexes with the LIM domains of lipoma-preferred partner in cell adhesion and migration dynamics PMID: 26945059
    3. two Ca2+-binding EF-hand motifs in the B"/PR72 subunit of protein phosphatase 2A demonstrating the ability or calcium ions to interact with and regulate PP2A PMID: 12524438
    4. The B''/PR72 subunit mediates Ca2+-dependent dephosphorylation of DARPP-32 by protein phosphatase 2A. PMID: 17535922
    5. PP2A can be targeted in a calcium-regulated manner to Cdc6 via the PR70 subunit, where it plays a role in regulating protein phosphorylation and stability. PMID: 18397887
    6. PR72 interacts physically and functionally with Naked cuticle. PR72, like Naked cuticle, acts as a negative regulator of the classical Wnt signaling cascade. PMID: 15687260

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  • 組織特異性：
    Expressed in heart, brain, placenta, lung, muscle and kidney.
  • 數據庫鏈接：

    HGNC: 9307

    OMIM: 604944

    KEGG: hsa:5523

    STRING: 9606.ENSP00000264977

    UniGene: Hs.518155



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