在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PPP1R7 Antibody, FITC conjugated

  • 中文名稱:
    PPP1R7兔多克隆抗體, FITC偶聯
  • 貨號:
    CSB-PA622999LC01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PPP1R7 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PPP1R7
  • 別名:
    PPP1R7 antibody; SDS22 antibody; Protein phosphatase 1 regulatory subunit 7 antibody; Protein phosphatase 1 regulatory subunit 22 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Protein phosphatase 1 regulatory subunit 7 protein (2-280AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    FITC
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Regulatory subunit of protein phosphatase 1.
  • 基因功能參考文獻:
    1. a Fra-1-miR-134 axis drives a positive feedback loop that amplifies ERK/JNK signaling and reduces chemosensitivity in ovarian cancer cells. PMID: 27685628
    2. Mechanistically, the phosphorylation of Sds22 by PLK1 strengthens the binding of Sds22 to PP1 and inhibits the dephosphorylation of Thr(232) of Aurora B to ensure a robust, error-free metaphase-anaphase transition. PMID: 27557660
    3. there is a second, parallel signalling pathway which triggers the relaxation of the polar cell cortex at mid anaphase--independent of furrow formation, centrosomes and microtubules, pathway depends on PP1 phosphatase and regulatory subunit Sds22 PMID: 26168397
    4. a model in which I3 regulates an SDS22-mediated PP1 activation step in solution that precedes SDS22 dissociation and transfer of PP1 to kinetochores, and which is required for PP1 to efficiently antagonize Aurora B. PMID: 25298395
    5. It was shown that Repo-Man and Sds22 contribute to timely Aurora B kinase substrate dephosphorylation on anaphase chromatin. PMID: 22801782
    6. human Sds22 is focally deleted and downregulated in multiple carcinomas, and this downregulation correlates with tumor progression, suggesting that sds22 inactivation may contribute to tumorigenesis and metastatic potential PMID: 21399659
    7. Sds22 specifically defines protein phosphatase 1 function and localization in mitosis. PMID: 20921135

    顯示更多

    收起更多

  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    SDS22 family
  • 組織特異性:
    Widely expressed.
  • 數據庫鏈接:

    HGNC: 9295

    OMIM: 602877

    KEGG: hsa:5510

    STRING: 9606.ENSP00000234038

    UniGene: Hs.36587



主站蜘蛛池模板: 亚洲中文字幕av无码区| 国产精品国产三级在线专区| 亚洲精品久久久久久久蜜臀老牛| 日韩av毛片无码免费| 2021自拍偷在线精品自拍偷| 熟女人妻水多爽中文字幕| 2020久久香蕉国产线看观看| 亚洲大尺度无码无码专线| 亚洲综合激情五月丁香六月| 亚洲国产精品成人午夜在线观看| 人人妻人人澡人人爽欧美一区| 中文文字幕文字幕亚洲色| 亚洲综合激情五月丁香六月| 欧美影院成年免费版| 天堂在/线资源中文在线| 国产成人精品三级在线影院| 动漫无遮挡h纯肉亚洲资源大片| 性色av一区二区三区无码| 国产熟妇高潮呻吟喷水| 国产 日韩 欧美 视频 制服| 国产成人精品av| 精品亚洲一区二区三区在线观看| 国产免费啪嗒啪嗒视频看看| 国产明星xxxx色视频| 熟妇人妻一区二区三区四区 | 丰满少妇作爱视频免费观看| 怀孕挺大肚子疯狂高潮av毛片| 国产精品白丝av网站在线观看| 亚洲成av人片一区二区| 97视频精品全国免费观看| 无遮挡18禁啪啪免费观看| 免费观看全黄做爰大片国产| 人人妻人人藻人人爽欧美一区| 亚洲午夜成人精品无码app| 日本国产制服丝袜一区| 波多野结衣av手机在线观看| 亚洲综合小说专区图片| 青青草99久久精品国产综合| 中文字幕精品亚洲无线码二区| 成人爱做日本视频免费| 国产午夜鲁丝片av无码免费|