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  4. PPP1R14B Antibody

PPP1R14B Antibody

  • 中文名稱：
    PPP1R14B兔多克隆抗體
  • 貨號：
    CSB-PA008762
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PPP1R14B
  • 別名：
    PHI 1 antibody; PHI1 antibody; Phospholipase C beta 3 neighboring gene protein antibody; Phospholipase C beta 3 neighbouring gene protein antibody; Phospholipase C-beta-3 neighbouring gene protein antibody; PLCB3N antibody; PNG antibody; PP14B_HUMAN antibody; Ppp1r14b antibody; Protein phosphatase 1 regulatory (inhibitor) subunit 14B antibody; Protein phosphatase 1 regulatory subunit 14B antibody; SOM172 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human PHI-1.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:100-1:300
    ELISA 1:20000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Inhibitor of PPP1CA. Has over 50-fold higher inhibitory activity when phosphorylated.
  • 基因功能參考文獻：
    1. Whereas CPI-17 staining was diffuse, PHI-1 was concentrated along the cell membrane in distinct foci. The common tissue distribution but different cellular localization of PHI-1 and CPI-17 suggest distinctive physiological roles for these PP1 inhibitors. PMID: 15083373
    2. PHI-1 participates in regulatory events at the trailing edge of migrating cells and modulates retraction of endothelial and epithelial cells PMID: 15522888
    3. An inhibitory phosphoprotein that inhibits the myosin- and glycogen-associated holoenzyme versions of protein type-1 phosphatase (PP1) as well as the monomeric catalytic subunit of PP1 in multiple tissues. PMID: 10606530
  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    PP1 inhibitor family
  • 組織特異性：
    Ubiquitous. Expressed at low levels.
  • 數據庫鏈接：

    HGNC: 9057

    OMIM: 601140

    KEGG: hsa:26472

    STRING: 9606.ENSP00000310117

    UniGene: Hs.523760



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