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中文名稱:
PPM1L兔多克隆抗體
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貨號:
CSB-PA087202
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規格:
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圖片:
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其他:
產品詳情
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產品名稱:
Rabbit anti-Homo sapiens (Human) PPM1L Polyclonal antibody
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Uniprot No.:
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基因名:
PPM1L
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宿主:
Rabbit
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反應種屬:
Human,Mouse
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免疫原:
Synthesized peptide derived from internal of Human PPM1L.
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免疫原種屬:
Homo sapiens (Human)
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克隆類型:
Polyclonal
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純化方式:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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濃度:
It differs from different batches. Please contact us to confirm it.
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產品提供形式:
Liquid
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應用范圍:
ELISA,WB
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推薦稀釋比:
Application |
Recommended Dilution |
WB |
1:500-1:3000 |
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Protocols:
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儲存條件:
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期:
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途:
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
靶點詳情
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功能:
Acts as a suppressor of the SAPK signaling pathways by associating with and dephosphorylating MAP3K7/TAK1 and MAP3K5, and by attenuating the association between MAP3K7/TAK1 and MAP2K4 or MAP2K6.
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基因功能參考文獻:
- Genetic variation at chromosome 3 harbors an element that regulates expression of an upstream candidate tumor suppressor, PPM1L, thus providing a novel mechanism for colorectal tumorigenesis. PMID: 19847890
- cloning and characterization of a novel human protein phosphatase 2C cDNA (PP2C epsilon*) PMID: 15560375
- These results suggest that PP2Cepsilon maintains ASK1 in an inactive state by dephosphorylation in quiescent cells, supporting the possibility that PP2Cepsilon and PP5 play different roles in H2O2-induced regulation of ASK1 activity. PMID: 17456047
- CERT is a physiological substrate of PP2Cepsilon and that dephosphorylation of CERT by PP2Cepsilon may play an important role in the regulation of ceramide trafficking from the ER to the Golgi apparatus. PMID: 18165232
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亞細胞定位:
Membrane; Single-pass type I membrane protein.
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蛋白家族:
PP2C family
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組織特異性:
Ubiquitous. Highly expressed in heart, placenta, lung, liver, kidney and pancreas.
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數據庫鏈接:
Most popular with customers