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Your Good Partner in Biology Research

POLE2 Antibody

  • 中文名稱:
    POLE2兔多克隆抗體
  • 貨號:
    CSB-PA004689
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of Jurkat cells using DNA pol ε B Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    DNA polymerase epsilon subunit 2 antibody; DNA polymerase epsilon subunit B antibody; DNA polymerase II subunit 2 antibody; DPE 2 antibody; DPE2 antibody; DPOE2_HUMAN antibody; POLE 2 antibody; POLE2 antibody; Polymerase (DNA directed) epsilon 2 (p59 subunit) antibody; Polymerase (DNA directed) epsilon 2 antibody; polymerase (DNA directed); epsilon 2; accessory subunit antibody; Polymerase; DNA; epsilon-2 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human DNA pol ε B.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:40000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Accessory component of the DNA polymerase epsilon complex. Participates in DNA repair and in chromosomal DNA replication.
  • 基因功能參考文獻:
    1. found that mutations occurred in POLE2 in 5 out of 16 cases of human colon cancer examined. PMID: 20065316
    2. The solution structure of the N-terminal domain of human DNA polymerase epsilon subunit B revealed a domain that consists of a left-handed superhelical bundle. PMID: 18676977
  • 亞細胞定位:
    Nucleus.
  • 蛋白家族:
    DNA polymerase epsilon subunit B family
  • 數據庫鏈接:

    HGNC: 9178

    OMIM: 602670

    KEGG: hsa:5427

    STRING: 9606.ENSP00000216367

    UniGene: Hs.162777



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