在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

POC1A Antibody

  • 中文名稱:
    POC1A兔多克隆抗體
  • 貨號:
    CSB-PA822753ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA822753ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human adrenal gland tissue using CSB-PA822753ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) POC1A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    POC1A
  • 別名:
    Pix2 antibody; POC1 centriolar protein homolog A (Chlamydomonas) antibody; POC1 centriolar protein homolog A antibody; Poc1a antibody; POC1A_HUMAN antibody; WD repeat containing protein 51A antibody; WD repeat domain 51A antibody; WD repeat-containing protein 51A antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human POC1 centriolar protein homolog A protein (138-407AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Plays an important role in centriole assembly and/or stability and ciliogenesis. Involved in early steps of centriole duplication, as well as in the later steps of centriole length control. Acts in concert with POC1B to ensure centriole integrity and proper mitotic spindle formation.
  • 基因功能參考文獻:
    1. we report the first patient with SOFT syndrome harboring compound heterozygous variants of POC1A. understanding POC1A mutations may provide appropriate management and genetic counseling to these patients and their families. PMID: 26791357
    2. Result identified a novel mutation in POC1A of patients with primordial dwarfism and showed that this mutation causes the formation of multiple numbers of centrioles and multipolar spindles with abnormal chromosome arrangement. PMID: 26162852
    3. POC1A may be added to ALMS1 and PCNT as examples of centrosomal or pericentriolar proteins whose dysfunction leads to extreme dyslipidaemic insulin resistance. PMID: 26336158
    4. Poc1A and Poc1B play redundant, but essential, roles in generation of stable centrioles, but Poc1B may have additional independent functions during cell cycle progression. PMID: 23015594
    5. Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis syndrome is caused by a POC1A mutation. PMID: 22840363
    6. POC1A truncation mutation causes a ciliopathy in humans characterized by primordial dwarfism. PMID: 22840364
    7. Based on these data, we propose that Pix1 and Pix2 are microtubule-associated adaptor proteins that likely contribute to a range of developmental and cell division processes. PMID: 18068700

    顯示更多

    收起更多

  • 相關疾病:
    Short stature, onychodysplasia, facial dysmorphism, and hypotrichosis (SOFT)
  • 亞細胞定位:
    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Cytoplasm, cytoskeleton, cilium basal body. Cytoplasm, cytoskeleton, spindle pole. Note=Component of both mother and daughter centrioles.
  • 蛋白家族:
    WD repeat POC1 family
  • 數據庫鏈接:

    HGNC: 24488

    OMIM: 614783

    KEGG: hsa:25886

    STRING: 9606.ENSP00000296484

    UniGene: Hs.476306



主站蜘蛛池模板: 激情偷乱人成视频在线观看| 国产无套精品一区二区三区| 国产产区一二三产区区别在线 | 另类亚洲综合区图片区小说| 国产v片在线播放免费无遮挡| 日韩精品射精管理在线观看| 国产精品av免费观看| 欧美亚洲综合成人a∨在线| 欧美变态另类牲交| 爱久久av一区二区三区| 50路60路老熟妇啪啪| 在线观看国产成人av片| 男女性爽大片视频免费看| 香蕉久久精品日日躁夜夜躁夏 | 国产精品免费福利久久| 国产精品久久久久久久久人妻| 久久综合97丁香色香蕉| 久久中文精品无码中文字幕下载| 丰满人妻中伦妇伦精品app| 国产精品国色综合久久| 亚洲 日韩 欧美 成人 在线| 午夜一区二区亚洲福利| 无码国产伦一区二区三区视频| 国产xxxxx在线观看| 真实国产精品视频400部| 把女邻居弄到潮喷的性经历| 摸丰满大乳奶水www免费| 久久激情日本亚洲欧洲国产中文| 无码视频免费一区二区三区| 欧美性色19p| 99精品国产一区二区| 99久久国产亚洲高清观看| 亚洲人成人网站在线观看| 九色九九九老阿姨| 国产在线无码不卡影视影院| 欧美白丰满老太aaa片| 亚洲老妇色熟女老太| 精品国产经典三级在线看| 顶级欧美熟妇高潮xxxxx| 亚洲国产中文在线二区三区免| 99久久无色码中文字幕|