在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PNRC2 Antibody

PNRC2 Antibody

  • 中文名稱：
    PNRC2兔多克隆抗體
  • 貨號：
    CSB-PA018290GA01HU
  • 規格：
    ￥3,900
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PNRC2
  • 別名：
    0610011E17Rik antibody; D4Bwg0593e antibody; FLJ20312 antibody; MGC11707 antibody; MGC93828 antibody; MGC99541 antibody; OTTMUSP00000010360 antibody; OTTMUSP00000010366 antibody; pnrc2 antibody; PNRC2_HUMAN antibody; Proline rich nuclear receptor coactivator 2 antibody; Proline-rich nuclear receptor coactivator 2 antibody; RP11-4M23.5 antibody; RP23-161N17.3 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse
  • 免疫原：
    Human PNRC2
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC,IF
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Involved in nonsense-mediated mRNA decay (NMD) by acting as a bridge between the mRNA decapping complex and the NMD machinery. May act by targeting the NMD machinery to the P-body and recruiting the decapping machinery to aberrant mRNAs. Required for UPF1/RENT1 localization to the P-body. Plays a role in glucocorticoid receptor-mediated mRNA degradation by interacting with the glucocorticoid receptor NR3C1 in a ligand-dependent manner when it is bound to the 5' UTR of target mRNAs and recruiting the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A, leading to RNA decay. Also acts as a nuclear receptor coactivator. May play a role in controlling the energy balance between energy storage and energy expenditure.
  • 基因功能參考文獻：
    1. UPF1 interacts with PNRC2 and that it triggers 5'-3' exonucleolytic decay of reporter transcripts in tethering assays. PNRC2 is probably an important mRNA decapping factor but that it does not appear to be required for nonsense-mediated mRNA decay. PMID: 29348139
    2. GR and PNRC2 interact in a ligand-dependent manner to recruit UPF1 for rapid mRNA degradation PMID: 25775514
    3. PNRC2 acts in synergy with Dcp1a to stimulate the decapping activity of Dcp2 by bridging the interaction between Dcp1a and Dcp2. PMID: 23085078
    4. Not only PNRC2 but also the corepressor TLE1 functioned as ERRgamma coactivator in a reporter gene analysis. PMID: 14651967
    5. PNRC2 plays an essential role in mammalian Nonsense-mediated mRNA decay (NMD), mediating the interaction between the NMD machinery and the decapping complex. PMID: 19150429

    顯示更多

    收起更多

  • 亞細胞定位：
    Nucleus. Cytoplasm, P-body.
  • 蛋白家族：
    PNRC family, PNRC2 subfamily
  • 組織特異性：
    Expressed in heart, lung, muscle and brain.
  • 數據庫鏈接：

    HGNC: 23158

    OMIM: 611882

    KEGG: hsa:55629

    STRING: 9606.ENSP00000383587

    UniGene: Hs.512636



主站蜘蛛池模板： 国产欧美va天堂在线电影| 久久久久亚洲精品男人的天堂| 在线观看国产成人av天堂| 久久人人妻人人爽人人爽| 精品丝袜国产自在线拍小草| 成年女人免费碰碰视频| 日本大片免a费观看视频| 国产精品视频一区二区亚瑟| 国产午夜理论不卡在线观看| 久久综合香蕉国产蜜臀av| 亚洲成熟女人毛毛耸耸多| 日韩精品无码久久久久久| 老子影院午夜伦不卡无码| 欧亚乱熟女一区二区在线| 少妇下蹲露大唇无遮挡| 五月激激激综合网亚洲| 久久精品无码一区二区www| 99re8这里有精品热视频免费| 亚洲色18禁成人网站www| 亚洲精品国产一区二区三| 狠狠色噜噜狠狠狠狠777米奇小说| 久久99亚洲精品久久99果| 久久久精品中文字幕麻豆发布| 久久熟妇人妻午夜寂寞影院| 欧美性猛交xxxx三人| 国产裸体美女永久免费无遮挡| 国产另类ts人妖一区二区| 亚洲欧美精品综合在线观看| 国产精品禁18久久久夂久| 亚洲狠狠婷婷综合久久| 亚洲欧美中文日韩在线视频一| 国产内射一区亚洲| 欧美性色黄大片手机版| 老湿机69福利区无码| 国产亚洲精品福利视频在线观看| 亚洲日韩欧美在线成人| 人妻无码久久久久久久久久久| 中文字幕av中文字无码亚| 日本一卡2卡3卡4卡免费乱码网站| 无码专区一va亚洲v专区在线 | 亚洲精品nv久久久久久久久久|