在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PNLIP Antibody

  • 中文名稱:
    PNLIP兔多克隆抗體
  • 貨號(hào):
    CSB-PA018262GA01HU
  • 規(guī)格:
    ¥3,900
  • 其他:

產(chǎn)品詳情

  • Uniprot No.:
  • 基因名:
  • 別名:
    lipase, pancreatic antibody; LIPP_HUMAN antibody; Pancreatic lipase antibody; Pancreatic triacylglycerol lipase antibody; PL antibody; PNLIP antibody; PNLIPD antibody; PTL antibody; Triacylglycerol acylhydrolase antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human,Mouse,Rat
  • 免疫原:
    Human PNLIP
  • 免疫原種屬:
    Homo sapiens (Human)
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA,WB,IHC
  • Protocols:
  • 儲(chǔ)存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能:
    Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones.
  • 基因功能參考文獻(xiàn):
    1. Serum lipase subtype analysis cannot replace the standard lipase measurement for the diagnosis of acute pancreatitis, but the test demonstrated adequate sensitivity for use in triage or as an add-on test for serum lipase elevation. PMID: 27243230
    2. Presence of methionine at position 221 in the PNLIP protein sequence causes protein misfolding and aggregation. PMID: 25862608
    3. All these findings support the use of YLLIP2 in enzyme replacement therapy for the treatment of pancreatic exocrine insufficiency, a pathological situation in which an acidification of intestinal contents occurs. PMID: 24650780
    4. In patients with intraductal papillary mucinous neoplasm without a history of pancreatitis, serum pancreatic lipase and amylase outside normal range are associated with risk of malignancy. PMID: 25239347
    5. a novel mutation in the PNLIP gene in two brothers with congenital pancreatic lipase deficiency PMID: 24262094
    6. Low PNLIP expression is associated with pancreatic cancer. PMID: 23918603
    7. Triacylglycerol lipase and alpha-amylase are highly over-expressed in pancreatic cyst fluids in patients with mucinous pancreatic neoplasms. PMID: 22393262
    8. Combination of two mutations with a promising one at the entrance of the catalytic cavity (K80E) negatively affected the lipase activity at neutral pH but not that at acidic pH. PMID: 20150178
    9. the amplitude of the lid opening measured in solution or in a frozen solution in the presence of amphiphiles PMID: 20136147
    10. Review. The structure and function of the pancreatic lipase C2 domains, based on the recent 3D structures and improved sequence alignments are reviewed. PMID: 12369922
    11. analysis of human pancreatic lipase from pancreatic juice (BCR693) and a recombinant form (BCR694) PMID: 12667003
    12. examination of tryptophan changes in pancreatic lipase PMID: 14580194
    13. a specific method of measuring classical pancreatic lipase in human serum PMID: 15316225
    14. analysis of a lid hydrophobicity pattern in pancreatic lipase PMID: 16179352
    15. pancreatic lipase-colipase interactions in the presence of bile salt micelles are mediated by Val-407 and Ile-408 of PL PMID: 16431912
    16. Electron paramagnetic resonance spectroscopy along with site-directed spin labeling was used to monitor the conformational changes in the human PL lid in solution to assess the effects of partners of the lipase, i.e. colipase and bile salts. PMID: 17269661
    17. Introducing a negative charge close to the catalytic histidine induced a shift of the pH optimum toward acidic values but strongly reduced the lipase activity. PMID: 18353248
    18. The disulfide bridge between the hinges of the lid kept the secondary structure of the lid intact, whereas the HPL was completely unfolded. PMID: 19113953
    19. Trp-107 and Trp-253 contribute to the change in steady state fluorescence that is triggered by mixed micelles of inhibitor and bile salt. PMID: 19346257

    顯示更多

    收起更多

  • 相關(guān)疾病:
    Pancreatic lipase deficiency (PNLIPD)
  • 亞細(xì)胞定位:
    Secreted.
  • 蛋白家族:
    AB hydrolase superfamily, Lipase family
  • 數(shù)據(jù)庫鏈接:

    HGNC: 9155

    OMIM: 246600

    KEGG: hsa:5406

    STRING: 9606.ENSP00000358223

    UniGene: Hs.501135



主站蜘蛛池模板: 日本成a人片在线播放| 美乳丰满人妻无码视频| 午夜成人影院网站18进| 亚洲精品国产高清一线久久| 性开放的欧美大片| 成人动漫综合网| 秋霞国产午夜伦午夜福利片| 曰本无码不卡高清av一二| 国产日韩在线视看高清视频手机| 又色又爽又黄的视频日本| 欧美激情a∨在线视频播放| 国产精品永久免费| 忘忧草日本在线www| 久久无码中文字幕免费影院| 国产成人无码午夜视频在线观看| 久久成人麻豆午夜电影| 亚洲精品久久久一二三区| 午夜成人亚洲理论片在线观看| 亚洲精品一区二区三区影院| 欧美老人巨大xxxx做受| 最近免费中文字幕大全免费版视频 | 精品丰满人妻无套内射| 国产精品久久久av久久久| 久久久久人妻一区二区三区vr | 婷婷成人丁香五月综合激情| 国产高清不卡免费视频| 久久99精品国产麻豆婷婷洗澡| 级r片内射在线视频播放| 男女真人国产牲交a做片野外 | 特级做a爰片毛片免费看108| 欧美人与动人物姣配xxxx| 日本丰满人妻xxxxxhd| 亚洲国产精品嫩草影院| 欲香欲色天天天综合和网| 亚洲欧美日韩愉拍自拍美利坚| 久久天天躁狠狠躁夜夜躁app| 自拍偷自拍亚洲精品播放| 精品夜夜爽欧美毛片视频| 伊人色综合网一区二区三区| 野花社区www视频最新资源| 亚洲国产一区二区三区在线观看|