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  4. PMRT15 Antibody, HRP conjugated

PMRT15 Antibody, HRP conjugated

Rare Species
  • 中文名稱：
    PMRT15兔多克隆抗體, HRP偶聯
  • 貨號：
    CSB-PA812747LB01DOA
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Arabidopsis thaliana PMRT15 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PMRT15
  • 別名：
    PMRT15 antibody; PMRT5 antibody; SKB1 antibody; At4g31120 antibody; F6E21.40Protein arginine N-methyltransferase 1.5 antibody; AtPMRT15 antibody; AtPMRT5 antibody; EC 2.1.1.319 antibody; Shk1 kinase-binding protein 1 homolog antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Arabidopsis thaliana
  • 免疫原：
    Recombinant Arabidopsis thaliana Protein arginine N-methyltransferase 1.5 protein (513-637AA)
  • 免疫原種屬：
    Arabidopsis thaliana
  • 標記方式：
    HRP
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Methylates arginine residues of myelin basic protein (MBP) in vitro. Methylates symmetrically histone H4 of the FLC chromatin to form H4R3me2s, which in turn suppresses FLC expression to induce flowering. Regulates alternative splicing by methylating spliceosomal proteins. Involved in the post-transcriptional regulation of the circadian clock.
  • 基因功能參考文獻：
    1. AtPRMT5 Regulates Shoot Regeneration through Mediating Histone H4R3 Dimethylation on KRPs and Pre-mRNA Splicing of RKP in Arabidopsis PMID: 27780782
    2. a new mechanism of plant root stem cell maintenance under DNA damage conditions that requires SKB1 PMID: 27090604
    3. Plants transduce stress-triggered NO signal to protein methylation machinery through S-nitrosylation of PRMT5 in response to environmental alterations. PMID: 28757206
    4. SKB1 and SKB1-mediated H4R3sme2 are required for the maintenance of SAM in Arabidopsis seedlings. PMID: 24349476
    5. A mutation in CAU1 significantly increased the expression level of the calcium signaling gene CAS, and functional disruption of CAS abolished the enhanced drought tolerance and stomatal [Ca(2+)]o signaling in cau1. PMID: 23943859
    6. SKB1 methylates the U6 snRNP LSM4 in response to salt stress and ABA. Loss of SKB1 influences pre-mRNA splicing. PMID: 21258002
    7. period lengthening associated with mutational disruption of prmt5 indicates that Rsme2 is a decoration important for the Arabidopsis clock PMID: 21097700
    8. key role for PRMT5 in the regulation of alternative splicing PMID: 20962777
    9. AtPRMT5 deficiency causes splicing defects in hundreds of genes involved in multiple biological processes. The splicing defects are identified in transcripts of several RNA processing factors involved in regulating flowering time. PMID: 20956294
    10. SKB1-mediated H4R3sme2 is a novel histone mark required for repression of FLC expression and flowering time control. PMID: 17363895
    11. involved in promotion of vegetative growth and FlOWERING LOCUS C-dependent flowering time regulation PMID: 17573539

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  • 亞細胞定位：
    Cytoplasm.
  • 蛋白家族：
    Class I-like SAM-binding methyltransferase superfamily, Protein arginine N-methyltransferase family
  • 組織特異性：
    Highly expressed in flowers, roots and siliques, lower expression in stems and mature leaves (at protein level). Abundant in shoot apex, young leaves and leaf primordia, floral and inflorescence meristems, gynoecium, stamens, sepals and young siliques, bu
  • 數據庫鏈接：

    KEGG: ath:AT4G31120

    STRING: 3702.AT4G31120.1

    UniGene: At.31771



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