在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNA1 Antibody, Biotin conjugated

PLXNA1 Antibody, Biotin conjugated

  • 中文名稱：
    PLXNA1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA14309D0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PLXNA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNA1 antibody; NOV antibody; PLXN1 antibody; Plexin-A1 antibody; Semaphorin receptor NOV antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Plexin-A1 protein (32-296AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
  • 基因功能參考文獻：
    1. Data suggest that Fyn tyrosine kinase (Fyn)-dependent phosphorylation at two critical tyrosines is a key feature of vertebrate plexin A1 (PlxnA1) and plexin A2 (PlxnA2) signal transduction. PMID: 29091353
    2. PLEXA1 has a developmental and tumor-associated pro-angiogenic role in brain neoplasms PMID: 27506939
    3. We thus screened 250 patients for the presence of mutations in PLXNA1, and identified different nonsynonymous mutations (p.V349L, p.V437L, p.R528W, p.H684Y, p.G720E, p.R740H, p.R813H, p.R840Q, p.A854T, p.R897H, p.L1464V, p.K1618T, p.C1744F), all at heterozygous state, in 15 patients. PMID: 28334861
    4. Semaphorin-3a, neuropilin-1 and plexin-A1 are axonal guidance molecules that have been recently implicated in regulating bone metabolism. PMID: 26602825
    5. a novel mutation in the PLXNA1 receptor (c.2587G>A) in newly established pancreatic cell line, is reported. PMID: 26962861
    6. Data indicate that plexin A1-4 (PLXNA1-4) mediation of neuroanatomical traits can be detected using in vivo neuroimaging techniques. PMID: 25518740
    7. neuropilin 1 and plexin A1 transmembrane domains interaction PMID: 24858828
    8. Expression of Plexin A1 in gastric carcinoma was significantly higher than that in normal gastric mucosa. PMID: 17520388
    9. Breast carcinoma cells support an autocrine pathway involving SEMA3A, plexin-A1, and NP1 that impedes their ability to chemotax. PMID: 14500350
    10. PlexinA1 may play an important role in the occurrence and development of gastric carcinoma, and be related to tumor angiogenesis and proliferation. PMID: 18161927
    11. In malignant pleural mesothelioma cells, plexin-A1 and VEGF-receptor 2 (VEGF-R2) are associated in a complex which are involved in survival pathways. PMID: 19176370
    12. Data show that the expression of Sema3A receptors (neuropilin-1 (NRP-1), NRP-2, plexin A1, plexin A2, and plexin A3) significantly increased during M-CSF-mediated differentiation of monocytes into macrophages. PMID: 19480842

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 組織特異性：
    Detected in fetal brain, lung, liver and kidney.
  • 數據庫鏈接：

    HGNC: 9099

    OMIM: 601055

    KEGG: hsa:5361

    STRING: 9606.ENSP00000377061

    UniGene: Hs.432329



主站蜘蛛池模板： 欧美性受xxxx狂喷水| 麻豆蜜桃av蜜臀av色欲av| 国产线观看免费观看| 久久人午夜亚洲精品无码区| 欧美成人精品第一区| 亚洲国产精品美女久久久久| 国产成人三级一区二区在线观看一| 精品乱码久久久久久中文字幕| 暖暖的在线观看日本社区| 日本丰满少妇bbb| 性一交一乱一乱一视频| 亚洲精品久久久久久久久久吃药| 日本新janpanese乱熟| 中文人妻熟妇乱又伦精品| 亚洲色大成网站www永久在线观看| 热99re久久精品这里都是精品免费| 人人超人人超碰超国产97超碰| 97色伦图片97综合影院 | 久久综合亚洲色hezyo社区| 免费观看又色又爽又黄的崩锅| 日韩 国产 变态另类 欧美| 大狠狠大臿蕉香蕉大视频| 精品国产亚洲一区二区三区在线观看| 人人妻人人爽人人做夜欢视频 | 国产美女遭强高潮网站下载| 天天狠天天透天干天天怕∴| 亚洲国产精品成人天堂| 激情久久亚洲小说| 女高中生自慰污污网站| 偷偷色噜狠狠狠狠的777米奇| 无码人妻一区二区三区在线视频| 国产精品老汉av| 久久www成人影院| 亚洲裸男gv网站| 成人无码一区二区三区| 女人张开双腿让男人猛桶| 四虎国产精品永久地址入口| 精品丝袜国产自在线拍小草| 亚洲国产精品嫩草影院| 8av国产精品爽爽ⅴa在线观看| 99久久无码一区人妻a黑|