在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PLXNA1 Antibody, Biotin conjugated

PLXNA1 Antibody, Biotin conjugated

  • 中文名稱：
    PLXNA1兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA14309D0Rb
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PLXNA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    PLXNA1 antibody; NOV antibody; PLXN1 antibody; Plexin-A1 antibody; Semaphorin receptor NOV antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Plexin-A1 protein (32-296AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Coreceptor for SEMA3A, SEMA3C, SEMA3F and SEMA6D. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
  • 基因功能參考文獻：
    1. Data suggest that Fyn tyrosine kinase (Fyn)-dependent phosphorylation at two critical tyrosines is a key feature of vertebrate plexin A1 (PlxnA1) and plexin A2 (PlxnA2) signal transduction. PMID: 29091353
    2. PLEXA1 has a developmental and tumor-associated pro-angiogenic role in brain neoplasms PMID: 27506939
    3. We thus screened 250 patients for the presence of mutations in PLXNA1, and identified different nonsynonymous mutations (p.V349L, p.V437L, p.R528W, p.H684Y, p.G720E, p.R740H, p.R813H, p.R840Q, p.A854T, p.R897H, p.L1464V, p.K1618T, p.C1744F), all at heterozygous state, in 15 patients. PMID: 28334861
    4. Semaphorin-3a, neuropilin-1 and plexin-A1 are axonal guidance molecules that have been recently implicated in regulating bone metabolism. PMID: 26602825
    5. a novel mutation in the PLXNA1 receptor (c.2587G>A) in newly established pancreatic cell line, is reported. PMID: 26962861
    6. Data indicate that plexin A1-4 (PLXNA1-4) mediation of neuroanatomical traits can be detected using in vivo neuroimaging techniques. PMID: 25518740
    7. neuropilin 1 and plexin A1 transmembrane domains interaction PMID: 24858828
    8. Expression of Plexin A1 in gastric carcinoma was significantly higher than that in normal gastric mucosa. PMID: 17520388
    9. Breast carcinoma cells support an autocrine pathway involving SEMA3A, plexin-A1, and NP1 that impedes their ability to chemotax. PMID: 14500350
    10. PlexinA1 may play an important role in the occurrence and development of gastric carcinoma, and be related to tumor angiogenesis and proliferation. PMID: 18161927
    11. In malignant pleural mesothelioma cells, plexin-A1 and VEGF-receptor 2 (VEGF-R2) are associated in a complex which are involved in survival pathways. PMID: 19176370
    12. Data show that the expression of Sema3A receptors (neuropilin-1 (NRP-1), NRP-2, plexin A1, plexin A2, and plexin A3) significantly increased during M-CSF-mediated differentiation of monocytes into macrophages. PMID: 19480842

    顯示更多

    收起更多

  • 亞細胞定位：
    Cell membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Plexin family
  • 組織特異性：
    Detected in fetal brain, lung, liver and kidney.
  • 數據庫鏈接：

    HGNC: 9099

    OMIM: 601055

    KEGG: hsa:5361

    STRING: 9606.ENSP00000377061

    UniGene: Hs.432329



主站蜘蛛池模板： 成人h动漫精品一区二区无码 | 亚洲欭美日韩颜射在线| 精品一卡二卡三卡四卡网站| 中文字幕人成无码人妻| 精品人伦一区二区三电影| 97se狼狼狼狼狼亚洲网| 日本强伦片中文字幕免费看| 国产精品成人99一区无码 | 欧美两根一起进3p在线观看| 永久免费男同av无码入口| 51国产黑色丝袜高跟鞋| 老熟女高潮喷水了| 人妻三级日本三级日本三级极| 亚洲精品国产情侣av在线| 久久久欧美国产精品人妻噜噜| 久久久久99精品国产片| 男男又爽又黄又无遮挡网站| 成人无码视频97免费| 国产女人精品视频国产灰线| 成人性做爰片免费视频| 日本中文字幕亚洲乱码| 最新亚洲中文字幕在线观看| 在线播放人成视频观看| 久久se精品一区精品二区| 色综合久久无码五十路人妻| 久久精品国产99久久6| 国产精品18久久久久久欧美| 久久天堂av综合合色蜜桃网| 色婷婷综合久久久久中文一区二区 | 日本少妇自慰免费完整版| 中文字幕乱码免费专区| 无码国产玉足脚交极品播放| 中文人妻av久久人妻18| 国产精品久久久久影院嫩草| 四虎影库在线永久影院免费观看| 亚洲综合色视频在线观看 | 欧美人与物videos另类| 在线日韩av免费永久观看| 日本大肚子孕妇交xxx| av天堂久久精品影音先锋| 永久免费男同av无码入口|