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  4. PLPBP Antibody, Biotin conjugated

PLPBP Antibody, Biotin conjugated

  • 中文名稱：
    PLPBP兔多克隆抗體, Biotin偶聯(lián)
  • 貨號：
    CSB-PA018755LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PLPBP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PLPBP
  • 別名：
    FLJ11861 antibody; Proline synthase co-transcribed bacterial homolog protein antibody; Proline synthetase co transcribed bacterial homolog antibody; Proline synthetase co transcribed homolog (bacterial) antibody; PROSC antibody; PROSC_HUMAN antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Pyridoxal phosphate homeostasis protein (1-275AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate (PLP), the active form of vitamin B6.
  • 基因功能參考文獻：
    1. We therefore confirm PROSC as a novel gene for vitamin-B6-dependent epilepsy and delineate a non-specific plasma vitamin B6 profile under pyridoxine treatment. PMID: 28391250
    2. Exploiting the universality of the Synechococcus elongatus COG0325 (PiPY) functions, it has been used in site-directed mutagenesis studies to shed light on disease causation by epilepsy-associated mutations in the human COG0325 gene PROSC. PMID: 28914444
    3. studies suggest that PROSC is involved in intracellular homeostatic regulation of pyridoxal 5'-phosphate, supplying this cofactor to apoenzymes while minimizing any toxic side reactions PMID: 27912044
  • 相關疾病：
    Epilepsy, early-onset, vitamin B6-dependent (EPVB6D)
  • 蛋白家族：
    Pyridoxal phosphate-binding protein YggS/PROSC family
  • 組織特異性：
    Ubiquitous.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 9457

    OMIM: 604436

    KEGG: hsa:11212

    STRING: 9606.ENSP00000333551

    UniGene: Hs.304792



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