在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PLIN3 Antibody

  • 中文名稱:
    PLIN3兔多克隆抗體
  • 貨號:
    CSB-PA954450
  • 規格:
    ¥1100
  • 圖片:
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA954450(PLIN3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA954450(PLIN3 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    PLIN3
  • 別名:
    47 kDa mannose 6-phosphate receptor-binding protein antibody; 47 kDa MPR binding protein antibody; 47 kDa MPR-binding protein antibody; Cargo selection protein TIP47 antibody; M6PRBP 1 antibody; M6PRBP1 antibody; Mannose 6 phosphate receptor binding protein 1 antibody; Mannose-6-phosphate receptor-binding protein 1 antibody; MGC11117 antibody; MGC2012 antibody; MPR binding protein 47 kDa antibody; Perilipin 3 antibody; Perilipin-3 antibody; Perilipin3 antibody; Placental protein 17 antibody; PLIN3 antibody; PLIN3_HUMAN antibody; pp17 antibody; Tail interacting protein 47 kD antibody; TIP47 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Synthetic peptide of Human PLIN3
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen affinity purification
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA,IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Required for the transport of mannose 6-phosphate receptors (MPR) from endosomes to the trans-Golgi network.
  • 基因功能參考文獻:
    1. High PLIN3 expression is associated with clear cell renal cell carcinoma. PMID: 29773494
    2. we found a DPP9-PPP6R3 fusion transcript in one tumor showing a matching genomic 11;19-translocation. Another tumor had a rearrangement of DPP9 with PLIN3. Both rearrangements were associated with diminished expression of the 3' end of DPP9 corresponding to the breakpoints identified by RNA-seq. PMID: 28893231
    3. Conserved amphipathic helices mediate lipid droplet targeting of PLIN1, PLIN2, and PLIN3. PMID: 26742848
    4. PLIN3 functions are intertwined with the lipogenic pathways implicated in sebaceous lipogenesis, such as desaturation and triglyceride synthesis. PMID: 25039349
    5. Postprandial triglyceride rich lipoproteins may be involved in atherosclerotic plaque formation through the regulation of perilipin-2 and perilipin-3 proteins in macrophages. PMID: 25595097
    6. Differential expression of PLIN3 and brefeldin A sensitivity may explain differential lipid oxidation efficiency in skeletal muscle among healthy lean, sedentary, and T2 diabetic males. PMID: 26171795
    7. Results indicate that microRNAs miR-148a and miR-30a, regulate Tail interacting protein of 47 kDa (TIP47) expression and lipid droplets (LD) in hepatitis C virus infected cells. PMID: 26170028
    8. Following exercise training, perilipin 3 protein expression was increased in the adipose tissue of women with polycystic ovary syndrome. PMID: 25342854
    9. Skeletal muscle perilipin 3 and coatomer proteins are increased following exercise and are associated with fat oxidation. PMID: 24632837
    10. Rab9-complexed TIP47 plays an essential role for the proper release of hepatitis C viral particles. PMID: 24480419
    11. PLIN3 is associated with the synthesis and secretion of PGE2 PMID: 23936516
    12. TIP47 plays an essential role in the life cycle of hepatitis C virus. PMID: 23354285
    13. studies identified the lipid droplet(LD-associated host protein, Tail-Interacting Protein 47 (TIP47) as a novel NS5A interaction partner; data support a model where TIP47-via its interaction with NS5A-serves as a novel cofactor for HCV infection possibly by integrating LD membranes into the membranous web PMID: 23593007
    14. TIP47 is here described for the first time as a viral restriction factor that acts by limiting viral protein synthesis. PMID: 23348195
    15. PLIN2-PLIN5 proteins were all more abundant in women than in men (p = 0.037 and p < 0.0001, respectively), consistent with higher intramyocellular lipid content in female skeletal muscle. PMID: 22667335
    16. Suppression of TIP47 in HeLa cells facilitated oxidative-stress-induced cell death. PMID: 20556887
    17. TIP47 is required for the encounter between Gag and Env, and thus for the generation of infectious HIV-1 particles from primary macrophages. PMID: 20070608
    18. can co-localize with lipid storage proteins PMID: 12077142
    19. Data show that placental protein 17b (PP17b)is a neutral lipid droplet-associated protein, and its expression is regulated by PKC- and PKA-dependent pathways PMID: 12631276
    20. TIP47 binding to HIV-1 envelope glycoprotein (ENV) is required for ENV transport to the trans-golgi network and for its incorportaion into virions and its pathogenicity PMID: 12768012
    21. Rab9 GTPase stability on late endosomes required interaction with TIP47 PMID: 15456905
    22. TIP47 and adipophilin are components of many, but not all, the lipid droplets in THP-1 cells PMID: 15545278
    23. we report the identity of an inhibitor, TIP47, which prevents retinylester hydrolysis catalyzed by GS2 lipase and hormone-sensitive lipase PMID: 16741517
    24. Binding of the effector protein TIP47 is important for Rab9 localization. PMID: 16769818
    25. The results suggested that the putative hydrophobic cleft is critical for the unique characteristics of TIP47. PMID: 16808905
    26. These results show that TIP47 is a cellular cofactor that plays an essential role in Env incorporation, allowing the encounter and the physical association between HIV-1 Gag and Env proteins during the viral assembly process. PMID: 17003132
    27. Adipophilin and TIP47 are expressed in LDs of vitamin A-storing hepatic stellate cells and additionally in lipid droplets of steatotic hepatocytes. PMID: 18393390
    28. The present results suggest that lipid droplets (LD) and LD-associated proteins have protective effects against apoptosis induced by fatty acid-bound albumin by sequestering free fatty acids. PMID: 18832575
    29. TIP47 (tail-interacting protein 47 kD) protein levels directly correlate with triglyceride levels; TIP47 may act as a carrier protein for free fatty acids and in this way participates in conversion of macrophages into foam cells PMID: 19286631
    30. VV p37 protein associates with host TIP47, Rab9 and CI-MPR. PMID: 19400954
    31. TIP47 has apolipoprotein-like properties and reorganizes liposomes into small lipid discs PMID: 19451273

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Lipid droplet.
  • 蛋白家族:
    Perilipin family
  • 數據庫鏈接:

    HGNC: 16893

    OMIM: 602702

    KEGG: hsa:10226

    STRING: 9606.ENSP00000221957

    UniGene: Hs.140452



主站蜘蛛池模板: 国产成人精品午夜福利在线播放| 久久不见久久见免费影院 | 好吊视频一区二区三区| 色猫咪av在线观看| 亚洲精品成人久久电影网 | 老色鬼永久精品网站| 欧美成人看片黄a免费看| 国产av精品毛片一区二区三区| 久久www成人看片免费不卡| 99久e在线精品视频在线 | 久久精品国产亚洲一区二区| 亚洲久热中文字幕在线| 无码被窝影院午夜看片爽爽jk| 无码播放一区二区三区| 国产乱子伦视频一区二区三区| 国产乱子伦视频在线播放| 日韩av无码一区二区三区不卡毛片| 国产精品久久久久久熟妇吹潮软件| 中文无码一区二区不卡αv| 亚洲不乱码卡一卡二卡4卡5| 日本wv一本一道久久香蕉| 中国china露脸自拍性hd| 级r片内射在线视频播放| 国产无夜激无码av毛片| 国产成人片无码免费视频软件| 人妻被按摩到潮喷中文不卡| 亚洲自偷自拍熟女另类| 人妻熟妇乱又伦精品视频| 日本熟妇色高清免费视频| 亚无码乱人伦一区二区| 日本成熟老妇乱| 国产成人精品一区二区视频| 亚洲一区二区av在线观看| 成年美女黄网站色奶头大全| 亚洲午夜性猛春交xxxx| 亚洲精品无码成人片| 国产欧美亚洲精品a第一页 | 新区乱码无人区二精东| 日本乱妇乱子视频| 97精品国产一区二区三区| 大学生久久香蕉国产线看观看|