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Your Good Partner in Biology Research

PKD1L2 Antibody, Biotin conjugated

  • 中文名稱:
    PKD1L2兔多克隆抗體, Biotin偶聯(lián)
  • 貨號:
    CSB-PA773589LD01HU
  • 規(guī)格:
    ¥880
  • 其他:

產(chǎn)品詳情

  • 產(chǎn)品名稱:
    Rabbit anti-Homo sapiens (Human) PKD1L2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PKD1L2
  • 別名:
    PKD1L2 antibody; KIAA1879 antibody; PC1L2 antibody; Polycystic kidney disease protein 1-like 2 antibody; PC1-like 2 protein antibody; Polycystin-1L2 antibody
  • 宿主:
    Rabbit
  • 反應(yīng)種屬:
    Human
  • 免疫原:
    Recombinant Human Polycystic kidney disease protein 1-like 2 protein (1-306AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標(biāo)記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產(chǎn)品提供形式:
    Liquid
  • 應(yīng)用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能:
    May function as an ion-channel regulator. May function as a G-protein-coupled receptor.
  • 基因功能參考文獻:
    1. Study found an association between a 6.2 kb dele- tion in the PKD1L2 gene and colorectal cancer in a Korean population. PMID: 27605020
    2. genes are mapped to chromosomes and gene structures are characterized; protein structure is predicted and contains strong ion channel signature motifs that suggest their possible function as components of cation channel pores PMID: 12782129
    3. PKD1L2 is expressed in the developing and adult heart and kidney. PMID: 15203210
    4. Ectopic expression of PKD1L2 in transgenic mice caused severe muscle atrophy. PMID: 19578180
  • 亞細(xì)胞定位:
    Membrane; Multi-pass membrane protein.
  • 蛋白家族:
    Polycystin family
  • 組織特異性:
    Expressed in all tissues tested including brain, placenta, mammary gland, testis, lung and liver. Highest expression in skeletal muscle. Isoform 2 is expressed in heart and kidney.
  • 數(shù)據(jù)庫鏈接:

    HGNC: 21715

    OMIM: 607894

    KEGG: hsa:114780

    STRING: 9606.ENSP00000469432

    UniGene: Hs.413525



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