在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PIP5K1B Antibody

PIP5K1B Antibody

  • 中文名稱：
    PIP5K1B兔多克隆抗體
  • 貨號：
    CSB-PA212653
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA212653(PIP5K1B Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA212653(PIP5K1B Antibody) at dilution 1/30, on the right is treated with fusion protein. (Original magnification: ×200)
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
  • 別名：
    MSS 4 antibody; MSS4 antibody; Phosphatidylinositol 4 phosphate 5 kinase type 1 beta antibody; Phosphatidylinositol-4-phosphate 5-kinase type I beta antibody; Phosphatidylinositol-4-phosphate 5-kinase type-1 beta antibody; PI4P5K 1 beta antibody; PI51B_HUMAN antibody; PIP5K1-beta antibody; PIP5K1B antibody; PIP5KIbeta antibody; Pipk 5 beta antibody; Pipk 5b antibody; Protein STM 7 antibody; Protein STM-7 antibody; PtdIns(4)P-5-kinase 1 beta antibody; STM 7 antibody; STM7 antibody; STM7 LSB antibody; Type I phosphatidylinositol 4 phosphate 5 kinase beta antibody; Type I phosphatidylinositol-4-phosphate 5-kinase beta antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human PIP5K1B
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    IHC 1:50-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Catalyzes the phosphorylation of phosphatidylinositol 4-phosphate (PtdIns(4)P/PI4P) to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2/PIP2), a lipid second messenger that regulates several cellular processes such as signal transduction, vesicle trafficking, actin cytoskeleton dynamics, cell adhesion, and cell motility. PtdIns(4,5)P2 can directly act as a second messenger or can be utilized as a precursor to generate other second messengers: inositol 1,4,5-trisphosphate (IP3), diacylglycerol (DAG) or phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3/PIP3). Mediates RAC1-dependent reorganization of actin filaments. Contributes to the activation of phospholipase PLD2. Together with PIP5K1A, is required, after stimulation by G-protein coupled receptors, for the synthesis of IP3 that will induce stable platelet adhesion.
  • 基因功能參考文獻：
    1. Data indicate that type I phosphatidylinositol 4-phosphate 5-kinase PIP5KIbeta mutants whose dimerization was impaired showed a severe decrease in PI(4,5)P2 production and plasma membrane delocalization. PMID: 25713054
    2. Knockdown of PIP5K1B in fibroblasts reproduced abnormal actin cytoskeleton remodeling evidenced in Friedreich's ataxia patient cells. PMID: 23552101
    3. Results identify PIPKIbeta as a novel regulator of focal adhesion disassembly and suggest that PIPKIbeta spatially regulates beta1 integrin endocytosis at adhesion sites to control cell migration. PMID: 20624912
    4. Results identify an isoform-specific PDZ-binding motif in PIP5KIbeta, which confers specificity for PIP5KIbeta signaling at the uropod during leukocyte chemotaxis. PMID: 20442317
    5. findings show that the human type I phosphatidylinositol 4-phosphate 5-kinase isoform beta (PIPKIbeta) has a role in organizing signaling at the cell rear PMID: 18158329
    6. Syk-dependent phosphorylation of PIP5K1B is the dominant modification responsible for the decrease in cellular phosphatidylinositol 4,5-bisphosphate. PMID: 19553680
    7. Observational study and genome-wide association study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator) PMID: 19850283

    顯示更多

    收起更多

  • 亞細胞定位：
    Cytoplasm, cytosol. Cell membrane. Endomembrane system.
  • 組織特異性：
    Detected in heart, pancreas, brain, kidney, skeletal muscle and lung.
  • 數據庫鏈接：

    HGNC: 8995

    OMIM: 602745

    KEGG: hsa:8395

    STRING: 9606.ENSP00000265382

    UniGene: Hs.534371



主站蜘蛛池模板： 亚洲日本中文字幕天天更新| 无码精品国产一区二区免费| 人妻少妇精品视频无码综合| 果冻传媒mv免费播放在线观看| 国产精品av一区二区三区不卡蜜 | 狠狠色噜噜狠狠狠狠97首创麻豆| 秋霞av鲁丝片一区二区| 国语自产偷拍精品视频蜜芽| 7777奇米成人狠狠成人影视| 热99re久久精品这里都是精品| 秋霞在线观看秋| 欧美三级欧美成人高清| 日本看片一二三区高清| 国产日韩欧美亚欧在线观看| 中文字幕亚洲一区二区三区| 日本高清视频在线www色| а天堂中文地址在线| 色综合色狠狠天天综合色| 国产三级在线观看免费| 亚洲中文字幕人成乱码| 一边捏奶一边高潮视频| 国产老熟女伦老熟妇露脸| 乱子轮熟睡1区| 色噜噜亚洲男人的天堂| 国产欧美日韩精品专区| 国产精品99久久99久久久动漫| 巨大黑人极品videos精品| 日本黄网站三级三级三级| 国产成人av一区二区三区无码| 国产麻无矿码直接观看| 亚洲男人av香蕉爽爽爽爽| 天堂а√中文最新版地址在线| 日本视频免费高清一本18| 国产成人国产在线观看| 国产精品第12页| 精品国产免费一区二区三区| 精品午夜中文字幕熟女人妻在线| 最新亚洲人成无码网站| 成在线人免费无码高潮喷水| 一本av高清一区二区三区| 久久精品人妻无码专区|