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  4. PIGK Antibody

PIGK Antibody

  • 中文名稱：
    PIGK兔多克隆抗體
  • 貨號(hào)：
    CSB-PA017974GA01HU
  • 規(guī)格：
    ￥3,900
  • 其他：

產(chǎn)品詳情

  • Uniprot No.：
  • 基因名：
    PIGK
  • 別名：
    PIGK antibody; GPI8 antibody; GPI-anchor transamidase antibody; GPI transamidase antibody; EC 3.-.-.- antibody; GPI8 homolog antibody; hGPI8 antibody; Phosphatidylinositol-glycan biosynthesis class K protein antibody; PIG-K antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human,Mouse,Rat
  • 免疫原：
    Human PIGK
  • 免疫原種屬：
    Homo sapiens (Human)
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA,WB,IHC
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    Mediates GPI anchoring in the endoplasmic reticulum, by replacing a protein's C-terminal GPI attachment signal peptide with a pre-assembled GPI. During this transamidation reaction, the GPI transamidase forms a carbonyl intermediate with the substrate protein.
  • 基因功能參考文獻(xiàn)：
    1. Report firstly demonstrated that inadequate protein-glycosylphosphatidylinositol anchoring caused by suppression of PIGK might affect the expression or function of some glycosylphosphatidylinositol-anchored proteins associated with tyrosinase activity. PMID: 27919619
    2. Our results demonstrate, for the first time, a link between the SNP 1048575 and low PIGK expression in CRC/HCC patients and also suggest a possible association between altered PIGK expression and disease susceptibility. PMID: 22824918
    3. GPI8 and PIG-T form a functionally important intermolecular disulfide bridge PMID: 12582175
  • 亞細(xì)胞定位：
    Endoplasmic reticulum membrane; Single-pass type I membrane protein.
  • 蛋白家族：
    Peptidase C13 family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8965

    OMIM: 605087

    KEGG: hsa:10026

    STRING: 9606.ENSP00000359848

    UniGene: Hs.178305



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