在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PHOX2A Antibody, Biotin conjugated

PHOX2A Antibody, Biotin conjugated

  • 中文名稱：
    PHOX2A兔多克隆抗體, Biotin偶聯(lián)
  • 貨號(hào)：
    CSB-PA017940LD01HU
  • 規(guī)格：
    ￥880
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PHOX2A Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PHOX2A
  • 別名：
    Aristaless homeobox (Drosophila) fibrosis of extraocular muscles congenital 2 autosomal recessive antibody; Aristaless homeobox gene homolog (Drosophila) antibody; Aristaless homeobox homolog antibody; Aristaless homeobox protein homolog antibody; ARIX 1 homeodomain protein antibody; ARIX antibody; Arix homeodomain protein antibody; ARIX1 homeodomain protein antibody; CFEOM 2 antibody; CFEOM2 antibody; FEOM 2 antibody; FEOM2 antibody; Fibrosis of extraocular muscles congenital 2 autosomal recessive antibody; MGC52227 antibody; NCAM 2 antibody; NCAM2 antibody; Paired like (aristaless) Homeobox 2A antibody; Paired like homeobox 2a antibody; Paired mesoderm homeobox 2a antibody; Paired mesoderm homeobox protein 2A antibody; Paired-like homeobox 2A antibody; PHOX 2A antibody; Phox2 antibody; Phox2a antibody; PHX2A_HUMAN antibody; Pmx 2a antibody; Pmx2 antibody; Pmx2a antibody
  • 宿主：
    Rabbit
  • 反應(yīng)種屬：
    Human
  • 免疫原：
    Recombinant Human Paired mesoderm homeobox protein 2A protein (150-264AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標(biāo)記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產(chǎn)品提供形式：
    Liquid
  • 應(yīng)用范圍：
    ELISA
  • Protocols：
  • 儲(chǔ)存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評(píng)價(jià)

靶點(diǎn)詳情

  • 功能：
    May be involved in regulating the specificity of expression of the catecholamine biosynthetic genes. Acts as a transcription activator/factor. Could maintain the noradrenergic phenotype.
  • 基因功能參考文獻(xiàn)：
    1. PHOX2A expression is finely controlled during retinoic acid differentiation and this, together with PHOX2B down-regulation. PMID: 26902400
    2. Genetic linkage was found at 11q13 between D11S4151 and D11S1320 and the PHOX2A gene. PMID: 22311481
    3. Patients with ARIX and/or PHOX2B polymorphisms had less hypoplastic superior oblique muscles. PMID: 22170461
    4. Mutations in the human ortholog of Aristaless cause X-linked mental retardation and epilepsy PMID: 11889467
    5. The paired-like homeodomain protein, Arix, mediates protein kinase A-stimulated dopamine beta-hydroxylase gene transcription through its phosphorylation status PMID: 11943777
    6. PHOX2A mutation analysis revealed a novel nonsense mutation in CFEOM2 (congenital fibrosis of extraocular muscles type 2) PMID: 14597037
    7. the polymorphisms of the ARIX gene and PHOX2B gene may be genetic risk factors for the development of congenital superior oblique muscle palsy PMID: 16049556
    8. PHOX2A, but not PHOX2B, seems to act directly on the c-RET promoter PMID: 16127999
    9. Together, these results suggest that phosphorylation of Arix by ERK1/2 inhibits its ability to interact with target genes, and that both specificity of expression and modulation by external stimuli are monitored through the same transcription factor. PMID: 16156742
    10. These results demonstrate the direct interactions of the Phox2a and b and dHAND transcription factors within a noradrenergic cell type PMID: 16280598
    11. the alpha3 subunit is expressed in every terminally differentiated ganglionic cell, this is the first example of a "pan-autonomic" gene whose expression is regulated by PHOX2 proteins. PMID: 17344216
    12. PHOX2A, like PHOX2B, is involved in the cascade leading to transcription factor TLX2 transactivation and presumably is involved in intestinal neuronal differentiation. PMID: 17505528
    13. a variant of Secretogranin II has a role in regulation by PHOX2 transcription factors and in hypertension PMID: 17584765
    14. The ARIX 153G>A polymorphism might be a genetic risk factor for the development of congenital superior oblique muscle palsy PMID: 18323871
    15. PHOX2A and PHOX2B genes are highly co-expressed in human neuroblastoma. PMID: 18949361
    16. PHOX2A gene, localized in a tumor suppressor candidate region at 11q, weas screened for mutations by DNA sequencing in 47 tumors of different stages. PMID: 19212675
    17. Transfection of Phox2a cDNA significantly increases mRNA and protein levels of norepinephrine transporter and dopamine beta-hydroxylase. PMID: 19573018
    18. Our 16-patient sample suggests that KIF21A and PHOX2A sequence variation does not have a role in common forms of congenital incomitant vertical strabismus. PMID: 19852579

    顯示更多

    收起更多

  • 相關(guān)疾病：
    Fibrosis of extraocular muscles, congenital, 2 (CFEOM2)
  • 亞細(xì)胞定位：
    Nucleus.
  • 蛋白家族：
    Paired homeobox family
  • 數(shù)據(jù)庫鏈接：

    HGNC: 691

    OMIM: 602078

    KEGG: hsa:401

    STRING: 9606.ENSP00000298231

    UniGene: Hs.731115



主站蜘蛛池模板： 国产亚洲欧美日韩精品一区二区| 乱色欧美激惰| 久久婷婷五月综合色和| 中文字幕久精品免费视频| 性饥渴少妇av无码毛片| 人妻互换免费中文字幕| 图片区小说区激情区偷拍区| 欧美人禽杂交狂配免费看| 国产亚洲精品a片久久久| 国产成人久久婷婷精品流白浆| 国产伦子沙发午休系列资源曝光 | 翘臀后进少妇大白嫩屁股| 久久中文精品无码中文字幕下载 | 极品嫩模高潮叫床| 久久久久久国产精品mv| 亚洲成 人 综合 亚洲欧洲| 精品国产aⅴ无码一区二区| 先锋影音xfyy5566男人资源| 免费观看国产小粉嫩喷水| 丁香婷婷综合激情五月色| 日日碰狠狠躁久久躁蜜桃| 99re6热精品视频在线观看| 天堂va视频一区二区| 国产精品无码无片在线观看| 欧美金妇欧美乱妇xxxx| 亚洲国产精品久久久天堂不卡海量| 又色又爽又黄高潮的免费视频| 成人免费一区二区三区| 亚洲欧美日韩成人一区二区三区| 少妇熟女久久综合网色欲| 亚洲毛片αv无线播放一区| 中文精品无码中文字幕无码专区| 免费国产成人高清在线观看网站| 欧美国产日韩a在线视频下载| 影音先锋人妻啪啪av资源网站| 免费观看潮喷到高潮中文字幕 | 国产午夜高潮熟女精品av软件 | 99999久久久久久亚洲| 又粗又大又黄又爽的免费视频| 熟妇人妻av无码一区二区三区| 亚洲国产精品嫩草影院永久 |