在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PHLDB2 Antibody, Biotin conjugated

  • 中文名稱:
    PHLDB2兔多克隆抗體, Biotin偶聯
  • 貨號:
    CSB-PA803110LD01HU
  • 規格:
    ¥880
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PHLDB2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PHLDB2
  • 別名:
    LL5 beta antibody; LL5B antibody; LL5beta antibody; PHLB2_HUMAN antibody; PHLDB2 antibody; Pleckstrin homology-like domain family B member 2 antibody; Protein LL5-beta antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Pleckstrin homology-like domain family B member 2 protein (734-1030AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Biotin
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Seems to be involved in the assembly of the postsynaptic apparatus. May play a role in acetyl-choline receptor (AChR) aggregation in the postsynaptic membrane.
  • 基因功能參考文獻:
    1. Prickle1 localized to the membrane through its farnesyl moiety, and the membrane localization was necessary for Prickle1 to regulate migration, to bind to CLASPs and LL5beta, and to promote microtubule targeting of focal adhesions. PMID: 27378169
    2. Collectively, our findings present the first to elucidate that miR-29c is a direct p53 target gene, and also identify PHLDB2 as an important miR-29c target gene involved in colon cancer metastasis. PMID: 28392396
    3. Liprin-alpha1, ERC1a and LL5 also define new highly polarized and dynamic cytoplasmic structures uniquely localized near the protruding cell edge PMID: 24982445
    4. These and other LL5beta-interacting proteins are associated with conventional podosomes in macrophages and podosome-like invadopodia in fibroblasts, strengthening the close relationship between synaptic and non-synaptic podosomes. PMID: 23525008
    5. minor allele, A, intronic single nucleotide polymorphism 'rs951660'in PHLDB2 might induce a delayed splicing and increase the susceptibility to Vascular dementia PMID: 22111664
    6. Signaling from laminin-integrin associations in epithelial cells attaches microtubule plus ends to the epithelial basal cell cortex via PHLDB1 and PHLDB2. PMID: 20513769
    7. LL5beta directs the translocation of filamin A and SHIP2 to sites of phosphatidylinositol 3,4,5-triphosphate (PtdIns(3,4,5)P3) accumulation, and PtdIns(3,4,5)P3 localization is mutually modified by co-recruited SHIP2. PMID: 20236936
    8. LL5beta and ELKS can form a PIP3-regulated cortical platform to which CLASPs attach distal microtubule ends. PMID: 16824950

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm. Membrane; Peripheral membrane protein. Note=Translocates to the plasma membrane at high levels of PtdIns(3,4,5)P3. At low levels of PtdIns(3,4,5)P3 is translocated to vesicular compartments.
  • 數據庫鏈接:

    HGNC: 29573

    OMIM: 610298

    KEGG: hsa:90102

    STRING: 9606.ENSP00000377502

    UniGene: Hs.603252



主站蜘蛛池模板: а天堂中文最新一区二区三区| 成人女人黄网站免费视频| 欧美阿v高清资源在线| 国产精品人人妻人人爽人人牛| 狠狠色综合7777久夜色撩人 | 超碰色偷偷男人的天堂| 亚洲色欲天天天堂色欲网| 黑人大战欲求不满人妻| 亚洲 欧美 中文 在线 视频| 欧美多人片高潮野外做片黑人| 成人无码免费视频在线播| 美女裸免费观看网站| 宅男噜噜噜66网站在线观看 | 男女同房做爰爽免费| 国产精品嫩草99av在线| 大色综合色综合网站| 国产高清av首播原创麻豆| 欧美肥胖老太vidio在线视频 | 国产精品免费精品自在线观看| 国产成人综合久久精品推下载| 亚洲春色av无码专区在线播放| 亚洲精品久久久久avwww潮水| 少妇内射高潮福利炮| 青青草国产精品一区二区| 免费啪视频在线观看视频网页| 精品成人av一区二区三区| 国产成人av一区二区三区在线| 久久久久久人妻毛片a片 | 亚洲日韩va在线视频| 日本精品高清一区二区 | 国产精品不卡无码av在线播放| 奇米影视7777狠狠狠狠色| av电影在线观看| 免费无码又爽又刺激高潮 | 免费又黄又爽1000禁片| 人妻一区二区三区高清av专区| 国产农村妇女高潮大叫| 日韩成人无码一区二区三区| 乱码视频午夜间在线观看| 亚洲嫩模喷白浆在线观看| 特黄特色大片免费播放|