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  4. PHKA1 Antibody, FITC conjugated

PHKA1 Antibody, FITC conjugated

  • 中文名稱：
    PHKA1兔多克隆抗體, FITC偶聯
  • 貨號：
    CSB-PA017922LC01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PHKA1 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    5330411D17 antibody; 9830108K24Rik antibody; kinase PHKA1 antibody; KPB1 antibody; KPB1_HUMAN antibody; MGC132604 antibody; Pcyt1b antibody; PHKA antibody; PHKA1 antibody; Phosphorylase b kinase regulatory subunit alpha antibody; Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform antibody; Phosphorylase kinase alpha M subunit antibody; phosphorylase kinase, alpha 1 (muscle) antibody; RP23 210E20.1 antibody; skeletal muscle isoform antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform protein (555-688AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    FITC
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
  • 基因功能參考文獻：
    1. muscle PHKA deficiency may present as an almost asymptomatic condition, despite a mild impairment of muscle PMID: 22238410
    2. alpha- and beta-subunits possess amino-terminal glucoamylase-like domains and suggests that they might possess a previously overlooked amylase activity PMID: 12876330
    3. X-linked PHK deficiency causes a mild metabolic myopathy with blunted muscle glycogen breakdown and impaired lactate production during dynamic exercise, which impairs oxidative capacity only marginally PMID: 18401027
  • 相關疾病：
    Glycogen storage disease 9D (GSD9D)
  • 亞細胞定位：
    Cell membrane; Lipid-anchor; Cytoplasmic side.
  • 蛋白家族：
    Phosphorylase b kinase regulatory chain family
  • 組織特異性：
    Muscle specific. Isoform 1 is predominant in vastus lateralis muscle. Isoform 2 predominates slightly in heart, and it predominates clearly in the other tissues tested.
  • 數據庫鏈接：

    HGNC: 8925

    OMIM: 300559

    KEGG: hsa:5255

    STRING: 9606.ENSP00000362643

    UniGene: Hs.201379



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