在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PHF5A Antibody

  • 中文名稱:
    PHF5A兔多克隆抗體
  • 貨號:
    CSB-PA017915EA01HU
  • 規格:
    ¥440
  • 圖片:
    • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA017915EA01HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA017915EA01HU at dilution of 1:100
    • Immunofluorescent analysis of Hela cells using CSB-PA017915EA01HU at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PHF5A Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PHF5A
  • 別名:
    1110007B08Rik antibody; Ac2 246 antibody; bK223H9.2 antibody; INI antibody; MGC1346 antibody; OTTHUMP00000198827 antibody; PHD finger 5a antibody; PHD finger like domain containing protein 5A antibody; PHD finger like domain protein 5A antibody; PHD finger protein 5A antibody; PHD finger-like domain protein 5A antibody; PHD finger-like domain-containing protein 5A antibody; Phf5a antibody; PHF5A_HUMAN antibody; Rds3 antibody; SAP14b antibody; SF3b14b antibody; Splicing factor 3B associated 14 kDa protein antibody; Splicing factor 3B-associated 14 kDa protein antibody; Transcription factor INI antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human PHD finger-like domain-containing protein 5A protein (1-110AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated

    本頁面中的產品,PHF5A Antibody (CSB-PA017915EA01HU),的標記方式是Non-conjugated。對于PHF5A Antibody,我們還提供其他標記。見下表:

    可提供標記
    標記方式 貨號 產品名稱 應用
    HRP CSB-PA017915EB01HU PHF5A Antibody, HRP conjugated ELISA
    FITC CSB-PA017915EC01HU PHF5A Antibody, FITC conjugated
    Biotin CSB-PA017915ED01HU PHF5A Antibody, Biotin conjugated ELISA
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    >95%, Protein G purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, IHC, IF
  • 推薦稀釋比:
    Application Recommended Dilution
    IHC 1:20-1:200
    IF 1:50-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Involved with the PAF1 complex (PAF1C) in transcriptional elongation by RNA polymerase II, and in regulation of development and maintenance of embryonic stem cell (ESC) pluripotency. Required for maintenance of ESCs self-renewal and cellular reprogramming of stem cells. Maintains pluripotency by recruiting and stabilizing PAF1C on pluripotency genes loci, and by regulating the expression of the pluripotency genes. Regulates the deposition of elongation-associated histone modifications, including dimethylated histone H3 'Lys-79' (H3K79me2) and trimethylated histone H3 'Lys-36' (H3K36me3), on PAF1C targets, self-renewal and pluripotency genes. Regulates RNA polymerase II promoter-proximal pause release of the PAF1C targets and self-renewal genes, and the levels of elongating ('Ser-2' phosphorylated) RNA polymerase II in their gene bodies. Regulates muscle specification in adult stem cells by stabilizing PAF1C in chromatin to promote myogenic differentiation. Involved in pre-mRNA splicing as a component of the splicing factor SF3B complex. SF3B complex is required for 'A' complex assembly formed by the stable binding of U2 snRNP to the branchpoint sequence (BPS) in pre-mRNA. Sequence independent binding of SF3A/SF3B complex upstream of the branch site is essential, it may anchor U2 snRNP to the pre-mRNA. Acts as a transcriptional regulator by binding to the GJA1/Cx43 promoter and enhancing its up-regulation by ESR1/ER-alpha.
  • 基因功能參考文獻:
    1. PHF5A-SF3B1 forms a central node for binding to splicing modulators PMID: 28541300
    2. We found PHF5A, a component of the U2 snRNP mRNA splicing factor, blocks expression from recombinant Adeno-associated virus vectors PMID: 26244496
    3. PHF5A facilitates recognition of exons with unusual C-rich 3' splice sites in thousands of essential genes PMID: 23651857
    4. The molecular and genetic research in this paper is performed on mouse but the paper identifies and discusses homologues found in human genomic sequence databases. PMID: 12054543
  • 亞細胞定位:
    Nucleus. Nucleus speckle.
  • 蛋白家族:
    PHF5 family
  • 數據庫鏈接:

    HGNC: 18000

    OMIM: 617846

    KEGG: hsa:84844

    STRING: 9606.ENSP00000216252

    UniGene: Hs.474980



主站蜘蛛池模板: h无码精品3d动漫在线观看| 无码熟熟妇丰满人妻啪啪 | 国产清纯白嫩初高生在线观看| 国产成久久免费精品av片| 国产精品久久久久蜜芽| 国产精品51麻豆cm传媒| 成人毛片无码免费播放网站| 久久亚洲色www成人男男| 亚洲成av人片天堂网站| 无码人妻精一区二区三区| 免费又黄又裸乳的视频| 精品av中文字幕在线毛片| 亚洲人成电影网站在线观看 | 中文字幕丝袜第1页| 无码av免费一区二区三区| 日日噜噜夜夜狠狠久久蜜桃| 99视频精品全部免费免费观看| 少妇人妻无码专区在线视频| 成在线人永久免费视频播放| 亚洲最大的成人网站| 无套内射chinesehd熟女| 国产精品久久久一区二区三区| 亚洲国产区男人本色| 亚洲成a∧人片在线播放无码| 亚洲337少妇裸体艺术| 影音先锋人妻av中文字幕久久 | 欧美成 人 网 站 免费| 免费无码鲁丝片一区二区| 日本人妻伦在线中文字幕| 999成人精品视频在线| 夜夜欢天天干| 久久久久国产综合av天堂| 亚洲人成人无码www| 亚瑟av亚洲精品一区二区| 欧美成人免费一区二区| 日韩精品无码一本二本三本| a毛片免费全部播放| 大伊香蕉精品一区视频在线 | 色欲精品国产一区二区三区av| 蜜芽av无码精品国产午夜| 日本熟妇中文字幕三级|