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  4. PGLYRP3 Antibody, Biotin conjugated

PGLYRP3 Antibody, Biotin conjugated

  • 中文名稱：
    PGLYRP3兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA017864LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PGLYRP3 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PGLYRP3
  • 別名：
    PGLYRP3 antibody; PGRPIA antibody; Peptidoglycan recognition protein 3 antibody; Peptidoglycan recognition protein I-alpha antibody; PGLYRPIalpha antibody; PGRP-I-alpha antibody; Peptidoglycan recognition protein intermediate alpha antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Peptidoglycan recognition protein 3 protein (90-222AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. Has bactericidal activity towards Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Binds also to Gram-negative bacteria, and has bacteriostatic activity towards Gram-negative bacteria. Plays a role in innate immunity.
  • 基因功能參考文獻：
    1. anti-inflammatory role in intestinal epithelial cells during antibacterial immune response PMID: 22099350
    2. expression of PGlyRP3 can be regulated by dietary factors such as probiotic oligosaccharides; PPARgamma is involved in regulation of expression of PGlyRP3 in intestinal mucosa by dietary components PMID: 21451128
    3. Data are consistent with previous reports of association of psoriasis with genes on 1q21, and suggest a role for Pglyrp3 in skin biology. PMID: 16362825
  • 亞細胞定位：
    Secreted.
  • 蛋白家族：
    N-acetylmuramoyl-L-alanine amidase 2 family
  • 組織特異性：
    Detected in skin epidermis, eccrine sweat glands and ducts, ciliary body epithelial cells of the eye, in small intestine, colon, stomach and in mature epithelial cells of the tongue (at protein level). Highly expressed in skin and esophagus, expressed als
  • 數據庫鏈接：

    HGNC: 30014

    OMIM: 608197

    KEGG: hsa:114771

    STRING: 9606.ENSP00000290722

    UniGene: Hs.348266



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