在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PGD Antibody

  • 中文名稱:
    PGD兔多克隆抗體
  • 貨號:
    CSB-PA030045
  • 規格:
    ¥1090
  • 圖片:
    • Western Blot analysis of A549 cells using PGD Polyclonal Antibody
  • 其他:

產品詳情

  • Uniprot No.:
  • 基因名:
    PGD
  • 別名:
    0610042A05Rik antibody; 6 phosphogluconate dehydrogenase; decarboxylating antibody; 6-phosphogluconate dehydrogenase antibody; 6PGD antibody; 6PGD_HUMAN antibody; AU019875 antibody; C78335 antibody; decarboxylating antibody; OTTMUSP00000011754 antibody; Pgd antibody; Phosphogluconate dehydrogenase antibody; RP23-249G3.4 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human,Mouse,Rat
  • 免疫原:
    Synthesized peptide derived from the Internal region of Human PGD.
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 抗體亞型:
    IgG
  • 純化方式:
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    WB, ELISA
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:500-1:2000
    ELISA 1:5000
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
  • 基因功能參考文獻:
    1. identified that 6-phosphogluconate dehydrogenase (6PGD) is critically involved in the development of anaplastic thyroid cancer (ATC) resistance to doxorubicin. 6PGD inhibition disrupts metabolic reprogramming in doxorubicin-resistant ATC cells. PMID: 29534964
    2. Studies indicate link between the 6-phosphogluconate dehydrogenase, oxidative pentose phosphate pathway (PPP) and lipogenesis through Ru-5-P-dependent inhibition of serine/threonine protein kinase LKB1-AMPK signalling. PMID: 26479318
    3. copy number gain of the PGD gene was consistently identified in cervical cancers but not in the normal tissues PMID: 24125036
    4. Results show that 6PGD activity is upregulated with increased lysine acetylation in primary leukemia cells from human patients, providing mechanistic insights into 6PGD upregulation in cancer cells. PMID: 25042803
    5. Expression of 6PGD positively correlates with advancing stage of lung carcinoma. Knockdown of 6PGD by shRNA potently inhibits c-Met tyrosine phosphorylation. PMID: 23973484
    6. Glycolytic cancer cells lacking 6-phosphogluconate dehydrogenase metabolize glucose to induce senescence PMID: 22677172
    7. Data suggest that the affinity of Nox2 for NADPH is increased in the presence of 6PGDH on cell stimulation. PMID: 21444627
    8. Hsa-miR-132 and -212 were negatively correlated with PGD in the prefrontal cortex of individuals affected with schizophrenia and bipolar disorders. PMID: 20675101

    顯示更多

    收起更多

  • 亞細胞定位:
    Cytoplasm.
  • 蛋白家族:
    6-phosphogluconate dehydrogenase family
  • 數據庫鏈接:

    HGNC: 8891

    OMIM: 172200

    KEGG: hsa:5226

    STRING: 9606.ENSP00000270776

    UniGene: Hs.464071



主站蜘蛛池模板: 狠狠亚洲色一日本高清色 | 少妇久久久久久被弄高潮 | 中文字幕丰满孑伦无码精品| 国产精品久久自在自线青柠| 国产aⅴ爽av久久久久久| 国产亚洲精品一区在线播放| 精品国产一区二区av麻豆| 96国产xxxx免费视频| 久久99精品久久久久婷婷| 欧美乱码精品一区二区三区| 青青草无码伊人久久| 亚洲精品无码久久久影院相关影片| 三级做爰高清视频| 色妞www精品视频| 99国产精品99久久久久久| 人妻激情偷乱一区二区三区| 2020最新无码福利视频| 亚洲高清乱码午夜电影网制服| 国产乱辈通伦影片在线播放亚洲| 一区二区免费高清观看国产丝瓜| 中文字幕无码一区二区免费| 三级做a全过程在线观看| 国内精品乱码卡一卡2卡麻豆 | 中文字幕v亚洲日本在线| 欧美丰满熟妇xxxx性ppx人| 人妻少妇精品一区二区三区| 欧美s码亚洲码精品m码| 欧美成人看片一区二区| 国产午精品午夜福利757视频播放| 国产高清在线精品一区下载| 国产精品免费看久久久| 美女露出奶头扒开尿口免费网站| 18处破外女出血在线| 亚洲不卡1卡2卡三卡入口| 中文字幕人成无码人妻综合社区| 伊人蕉久中文字幕无码专区| 尹人香蕉久久99天天拍欧美p7| 久久综合九色综合欧洲98| 少妇高潮毛片免费看| www国产精品内射| 日韩午夜理论免费tv影院|