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  4. PFDN2 Antibody, Biotin conjugated

PFDN2 Antibody, Biotin conjugated

  • 中文名稱：
    PFDN2兔多克隆抗體, Biotin偶聯
  • 貨號：
    CSB-PA017813LD01HU
  • 規格：
    ￥880
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PFDN2 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PFDN2
  • 別名：
    OTTHUMP00000029707 antibody; PFD2 antibody; PFD2_HUMAN antibody; PFDN2 antibody; prefoldin 2 antibody; Prefoldin subunit 2 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Prefoldin subunit 2 protein (1-154AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Biotin
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    >95%, Protein G purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Preservative: 0.03% Proclin 300
    Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Binds specifically to cytosolic chaperonin (c-CPN) and transfers target proteins to it. Binds to nascent polypeptide chain and promotes folding in an environment in which there are many competing pathways for nonnative proteins.
  • 基因功能參考文獻：
    1. prefoldin is amplified at 1q23.3-q24.1 in bladder cancer PMID: 23914742
    2. knockdown of PFD2 and PFD5 disrupted prefoldin formation in HTT-expressing cells, resulting in accumulation of aggregates of a pathogenic form of HTT and in induction of cell death. PMID: 23720755
    3. Is part of an RNA polymerase II-associated complex with possible chaperone activity. PMID: 19450687
  • 亞細胞定位：
    Nucleus. Cytoplasm. Mitochondrion.
  • 蛋白家族：
    Prefoldin subunit beta family
  • 數據庫鏈接：

    HGNC: 8867

    OMIM: 613466

    KEGG: hsa:5202

    STRING: 9606.ENSP00000356989

    UniGene: Hs.492516



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