在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PEX7 Antibody

PEX7 Antibody

  • 中文名稱：
    PEX7兔多克隆抗體
  • 貨號：
    CSB-PA017808ESR2HU
  • 規(guī)格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human breast cancer using CSB-PA017808ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using CSB-PA017808ESR2HU at dilution of 1:100
  • 其他：

產(chǎn)品詳情

  • 產(chǎn)品名稱：
    Rabbit anti-Homo sapiens (Human) PEX7 Polyclonal antibody
  • Uniprot No.：
  • 基因名：
    PEX7
  • 別名：
    PBD9B antibody; PCDP1 antibody; Peroxin 7 antibody; Peroxin-7 antibody; Peroxisomal PTS2 receptor antibody; Peroxisomal targeting signal 2 receptor antibody; Peroxisome biogenesis factor 7 antibody; Peroxisome targeting signal 2 receptor antibody; PEX7 antibody; PEX7 protein antibody; PEX7_HUMAN antibody; PTS2 receptor antibody; PTS2R antibody; RCDP1 antibody; RD antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Peroxisomal targeting signal 2 receptor protein (1-240AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產(chǎn)品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產(chǎn)品評價

靶點詳情

  • 功能：
    Binds to the N-terminal PTS2-type peroxisomal targeting signal and plays an essential role in peroxisomal protein import.
  • 基因功能參考文獻：
    1. This revealed a marked plasmalogen deficiency and a deficient fatty acid alpha-oxidation in the IHH cells, due to a defect of PEX7, a cytosolic receptor protein required for peroxisomal import of a subset of peroxisomal proteins. PMID: 28013369
    2. our data suggest that insertion of the trimeric PEX5-PEX7-PTS2 protein complex into the DTM is probably accompanied by conformational alterations in PEX5 to allow release of the PTS2 protein into the organelle matrix PMID: 26138649
    3. Mutation in the PEX7 Gene is associated with Rhizomelic Chondrodysplasia Punctata Type 1. PMID: 25800479
    4. the sequential formation of a highly stable trimeric complex involving cargo protein, PEX7 and PEX5L stabilizes cargo binding and is a prerequisite for PTS2-mediated peroxisomal import. PMID: 25538232
    5. dysfunctional Pex7p, including mutants from RCDP patients, is degraded by a ubiquitin-dependent proteasomal pathway involving the CRL4A (Cullin4A-RING ubiquitin ligase) complex. PMID: 24989250
    6. Export of peroxisomal PEX7 back into the cytosol requires export of PEX5. PMID: 24865970
    7. This results of this studt revealed the association of 2 single nucleotide polymorphisms and 1 haplotype with autism spectrum disorder (P < .05). PMID: 22378669
    8. Structural requirements for interaction of peroxisomal targeting signal 2 and its receptor PEX7. PMID: 22057399
    9. Mutations in PEX7 gene is associated with Rhizomelic chondrodysplasia punctata. PMID: 20145307
    10. mutational spectrum in the PEX7 gene of 78 patients (including five pairs of sibs) clinically and biochemically diagnosed with RCDP type I PMID: 11781871
    11. Functional studies on human Pex7p: subcellular localization and interaction with proteins containing a peroxisome-targeting signal type 2 and other peroxins. PMID: 11931631
    12. The residual activity of mutant Pex7 protein in rhizomelic chondrodysplasia punctata patients and reduced amounts of normal Pex7 are associated with milder and variant phenotypes. PMID: 12325024
    13. This gene codes for the peroxin 7 receptor protein required for peroxisomal import of proteins containing a peroxisomal targeting signal type 2. Mutations may result in a broad clinical spectrum of Refsum disease. PMID: 12522768
    14. Identification of PEX7 as the second gene involved in Refsum disease. PMID: 14713215
    15. Missense mutations, sequence duplications and deletions in PRX7 in 3 patients with the Refsum disease phenotypes. PMID: 14974078

    顯示更多

    收起更多

  • 相關疾病：
    Peroxisome biogenesis disorder complementation group 11 (PBD-CG11); Rhizomelic chondrodysplasia punctata 1 (RCDP1); Peroxisome biogenesis disorder 9B (PBD9B)
  • 亞細胞定位：
    Peroxisome. Cytoplasm.
  • 蛋白家族：
    WD repeat peroxin-7 family
  • 組織特異性：
    Ubiquitous. Highest expression in pancreas, skeletal muscle and heart.
  • 數(shù)據(jù)庫鏈接：

    HGNC: 8860

    OMIM: 215100

    KEGG: hsa:5191

    STRING: 9606.ENSP00000315680

    UniGene: Hs.280932



主站蜘蛛池模板： 色妞ww精品视频7777| 色欲色香天天天综合网站| 综合 欧美 小说 另类 图| 国产大片黄在线观看私人影院| 欧美精品久久天天躁| 羞羞色男人的天堂| 国产香蕉国产精品偷在线| 国产人成高清在线视频99最全资源 | 国产情侣疯狂作爱系列| 丰满少妇做爰视频爽爽和| 亚洲日韩一区二区三区| 久久精品国产亚洲精品| _97夜夜澡人人爽人人喊_欧美| 国产无遮挡又黄又爽奶头| 欧洲av无码放荡人妇网站| 艳妇臀荡乳欲伦交换h在线观看| 色哟哟网站在线观看| 影音先锋日日狠狠久久| 亚洲综合久久一本久道| 又大又长粗又爽又黄少妇视频| 偷偷要色偷偷中文无码| 无码人妻在线一区二区三区免费| 亚洲精品www久久久| 无码人妻精品一区二区三区久久久| 国产精品人妻久久毛片高清无卡| 国产在线精品一品二区| 亚洲人成亚洲人成在线观看| 国产精品久久久国产盗摄| 97色伦97色伦国产欧美| 一本色道久久99一综合| 国产sm主人调教女m视频| 最近中文字幕免费mv在线| 国产乱码二卡3卡四卡| 亚洲色偷精品一区二区三区| 日本公与熄乱理在线播放| 国产做a爰片久久毛片a片美国| 国产精品国产三级国产专区53| 国产超碰人人爱被ios解锁| 狠狠噜狠狠狠狠丁香五月| 蜜桃视频无码区在线观看| 亚洲乱亚洲乱妇无码|