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  4. PEX10 Antibody

PEX10 Antibody

  • 中文名稱：
    PEX10兔多克隆抗體
  • 貨號：
    CSB-PA030039
  • 規格：
    ￥1090
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PEX10
  • 別名：
    AV128229 antibody; Gm142 antibody; MGC1998 antibody; NALD antibody; OTTHUMP00000001658 antibody; PBD6A antibody; PBD6B antibody; peroxin 10 antibody; Peroxin-10 antibody; Peroxisomal biogenesis factor 10 antibody; Peroxisome assembly protein 10 antibody; Peroxisome biogenesis factor 10 antibody; PEX10 antibody; PEX10_HUMAN antibody; RING finger protein 69 antibody; RNF69 antibody; RP23-298E4.1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Synthesized peptide derived from the Internal region of Human Peroxin 10.
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    WB, IHC, ELISA
  • 推薦稀釋比：
    Application Recommended Dilution
    WB 1:500-1:2000
    IHC 1:100-1:300
    ELISA 1:40000
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Somewhat implicated in the biogenesis of peroxisomes.
  • 基因功能參考文獻：
    1. This study demonstrated that two mutations in PEX10 were found in the three peroxisomal biogenesis disorders patients: c.827G>T (novel) causing the missense change p.Cys276Phe and c.932G>A causing the missense change p.Arg311Gln. PMID: 27230853
    2. abnormal expression of PEX10 gene resulting from copy number variations of 1p36 region may be associated with the epilepsy phenotype PMID: 25636090
    3. child and an adult of normal intelligence with progressive ataxia, axonal motor neuropathy, decreased vibration sense and cerebellar atrophy; 2 mutations in PEX10 found in child, c.992G>A and c.764_765insA, and in the adult, c.2T>C and c.790C>T PMID: 20695019
    4. Genetic heterogeneity in Japanese patients with peroxisome biogenesis disorders and evidence for a founder haplotype for the most common mutation in PEX10 gene. PMID: 14713216
    5. the relative fraction of disease-causing alleles that occur in the coding and splice junction sequences of PEX10 gene. PMID: 19105186

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  • 相關疾病：
    Peroxisome biogenesis disorder complementation group 7 (PBD-CG7); Peroxisome biogenesis disorder 6A (PBD6A); Peroxisome biogenesis disorder 6B (PBD6B)
  • 亞細胞定位：
    Peroxisome membrane; Peripheral membrane protein.
  • 蛋白家族：
    Pex2/pex10/pex12 family
  • 數據庫鏈接：

    HGNC: 8851

    OMIM: 602859

    KEGG: hsa:5192

    UniGene: Hs.732228



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