在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

  1. Home
  2. 抗體
  3. 多克隆抗體
  4. PEF1 Antibody

PEF1 Antibody

  • 中文名稱：
    PEF1兔多克隆抗體
  • 貨號：
    CSB-PA289634
  • 規格：
    ￥1100
  • 圖片：
    • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA289634(PEF1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA289634(PEF1 Antibody) at dilution 1/20, on the right is treated with fusion protein. (Original magnification: ×200)
    • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: Jurkat cells, hela cells, 293T cells, human thyroid cancer tissue, Primary antibody: CSB-PA289634(PEF1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds
  • 其他：

產品詳情

  • Uniprot No.：
  • 基因名：
    PEF1
  • 別名：
    ABP32 antibody; PEF antibody; PEF protein with a long N terminal hydrophobic domain antibody; PEF protein with a long N-terminal hydrophobic domain antibody; pef1 antibody; PEF1_HUMAN antibody; PEF1A antibody; Peflin antibody; Penta EF hand domain containing protein 1 antibody; Penta-EF hand domain-containing protein 1 antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human,Mouse,Rat
  • 免疫原：
    Fusion protein of Human PEF1
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen affinity purification
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA,WB,IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    ELISA 1:2000-1:5000
    WB 1:500-1:2000
    IHC 1:25-1:100
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Calcium-binding protein that acts as an adapter that bridges unrelated proteins or stabilizes weak protein-protein complexes in response to calcium. Together with PDCD6, acts as calcium-dependent adapter for the BCR(KLHL12) complex, a complex involved in endoplasmic reticulum (ER)-Golgi transport by regulating the size of COPII coats. In response to cytosolic calcium increase, the heterodimer formed with PDCD6 interacts with, and bridges together the BCR(KLHL12) complex and SEC31 (SEC31A or SEC31B), promoting monoubiquitination of SEC31 and subsequent collagen export, which is required for neural crest specification. Its role in the heterodimer formed with PDCD6 is however unclear: some evidence shows that PEF1 and PDCD6 work together and promote association between PDCD6 and SEC31 in presence of calcium. Other reports show that PEF1 dissociates from PDCD6 in presence of calcium, and may act as a negative regulator of PDCD6. Also acts as a negative regulator of ER-Golgi transport; possibly by inhibiting interaction between PDCD6 and SEC31.
  • 基因功能參考文獻：
    1. This work identifies for the first time a clear steady state role for a PEF protein in ER-to-Golgi transport-peflin is a negative regulator of transport. PMID: 27276012
    2. peflin is stabilized by dimerization through its fifth EF-hand region PMID: 11883899
  • 亞細胞定位：
    Cytoplasm. Endoplasmic reticulum. Membrane; Peripheral membrane protein. Cytoplasmic vesicle, COPII-coated vesicle membrane; Peripheral membrane protein.
  • 數據庫鏈接：

    HGNC: 30009

    OMIM: 610033

    KEGG: hsa:553115

    STRING: 9606.ENSP00000362807

    UniGene: Hs.470417



主站蜘蛛池模板： 亚洲愉拍自拍另类天堂| 各种少妇正面bbw撒尿| 欧洲精品久久久av无码电影| 久久综合伊人77777| 88国产精品欧美一区二区三区| 亚洲欧美中文日韩在线视频一| 国产性猛交普通话对白| 日韩精品人妻系列一区二区三区| 国产乱人伦偷精品视频免| 久久久久久亚洲综合影院| 人妻熟女一区二区三区app下载 | 国产三级在线观看完整版| 在线播放国产一区二区三区| 国精品人妻无码一区二区三区d3 | 伊人中文字幕无码专区| 日本在线视频www鲁啊鲁| 狠狠的干性视频| 校园春色~综合网| 人人人爽人人爽人人av| 国产成人亚洲综合色婷婷秒播| 东京热人妻丝袜av无码| 久久精品国产一区二区三区不卡 | 色猫咪免费人成网站在线观看| 久久99亚洲精品久久69| 精品无码国产自产拍在线观看| 久久婷婷五月综合色中文字幕| 日韩精品人妻系列无码专区 | av激情亚洲男人的天堂| 色婷婷亚洲一区二区综合| 成人片黄网站色大片免费毛片| 亚洲精品一品区二品区三品区| 亚洲欧美色αv在线影视| 国产福利无码一区在线| 国产精品女视频一区二区| 国产精品久久久久久久久久久久午夜片 | 欧美人与动牲交aⅴ| 久久精品国产精品亚洲| 国产男生午夜福利免费网站| 成人a大片在线观看| 亚洲日本成本人观看| 精品国产乱码久久久久久1区2区|