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PDHA2 Antibody

  • 中文名稱:
    PDHA2兔多克隆抗體
  • 貨號:
    CSB-PA017716ESR2HU
  • 規格:
    ¥440
  • 圖片:
    • Western blot
      All lanes: PDHA2 antibody at 1.9µg/ml
      Lane 1: Mouse gonadal tissue
      Lane 2: 293T whole cell lysate
      Lane 3: A549 whole cell lysate
      Lane 4: HepG2 whole cell lysate
      Secondary
      Goat polyclonal to rabbit IgG at 1/10000 dilution
      Predicted band size: 43 kDa
      Observed band size: 43 kDa
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA017716ESR2HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human prostate cancer using CSB-PA017716ESR2HU at dilution of 1:100
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PDHA2 Polyclonal antibody
  • Uniprot No.:
  • 基因名:
  • 別名:
    PDHA2 antibody; PDHAL antibody; Pyruvate dehydrogenase E1 component subunit alpha antibody; testis-specific form antibody; mitochondrial antibody; EC 1.2.4.1 antibody; PDHE1-A type II antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human, Mouse
  • 免疫原:
    Recombinant Human Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial protein (119-388AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA, WB, IHC
  • 推薦稀釋比:
    Application Recommended Dilution
    WB 1:1000-1:5000
    IHC 1:20-1:200
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and thereby links the glycolytic pathway to the tricarboxylic cycle.
  • 基因功能參考文獻:
    1. Our results indicated that miR215p targeted PDHA1 to regulate a metabolic switch and cancer progression in gastric cancer, and reveal the potential role of the miR215p/PDHA1 axis in gastric cancer treatment PMID: 30226598
    2. Methylation of the PDHA2 coding region can inhibit gene transcription. PMID: 22675509
    3. it is the full demethylation of the CpG island located in the coding region that seems to play a crucial role upon PDHA2 gene transcription in testis. PMID: 20005141
  • 亞細胞定位:
    Mitochondrion matrix.
  • 組織特異性:
    Testis. Expressed in postmeiotic spermatogenic cells.
  • 數據庫鏈接:

    HGNC: 8807

    OMIM: 179061

    KEGG: hsa:5161

    STRING: 9606.ENSP00000295266

    UniGene: Hs.131361



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