在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

PDE6B Antibody

  • 中文名稱:
    PDE6B兔多克隆抗體
  • 貨號:
    CSB-PA2104ESR1HU
  • 規格:
    ¥440
  • 其他:

產品詳情

  • 產品名稱:
    Rabbit anti-Homo sapiens (Human) PDE6B Polyclonal antibody
  • Uniprot No.:
  • 基因名:
    PDE6B
  • 別名:
    5''-cyclic phosphodiesterase subunit beta antibody; Congenital stationary night blindness 3 autosomal dominant antibody; CSNB 3 antibody; CSNB3 antibody; CSNBAD2 antibody; GMP PDE beta antibody; GMP-PDE beta antibody; PDE 6 beta antibody; PDE 6B antibody; PDE6B antibody; PDE6B_HUMAN antibody; PDEB antibody; Phosphodiesterase 6B antibody; Phosphodiesterase 6B cGMP specific rod beta antibody; Rd 1 antibody; Rd1 antibody; Rod cGMP phosphodiesterase beta subunit antibody; Rod cGMP specific 3' 5' cyclic phosphodiesterase beta subunit antibody; Rod cGMP-specific 3'' antibody; RP40 antibody
  • 宿主:
    Rabbit
  • 反應種屬:
    Human
  • 免疫原:
    Recombinant Human Rod cGMP-specific 3\',5\'-cyclic phosphodiesterase subunit beta protein (1-190AA)
  • 免疫原種屬:
    Homo sapiens (Human)
  • 標記方式:
    Non-conjugated
  • 克隆類型:
    Polyclonal
  • 抗體亞型:
    IgG
  • 純化方式:
    Antigen Affinity Purified
  • 濃度:
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液:
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式:
    Liquid
  • 應用范圍:
    ELISA
  • Protocols:
  • 儲存條件:
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期:
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途:
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能:
    Necessary for the formation of a functional phosphodiesterase holoenzyme. Involved in retinal circadian rhythm photoentrainment via modulation of UVA and orange light-induced phase-shift of the retina clock. May participate in processes of transmission and amplification of the visual signal.
  • 基因功能參考文獻:
    1. Heterozygous mutation in the PDE6B gene can cause a reduction in the rod function to different degrees. PMID: 25827439
    2. Next-generation whole exome sequencing revealed a homozygous c.1923_1969ins6del47 nonsense PDE6B mutation, which has not been previously described, that segregated with the disease in the family. PMID: 24828262
    3. The family was found to segregate novel mutations of two different genes: myosin VIIA (MYO7A), and phosphodiesterase 6B, which causes nonsyndromic retinitis pigmentosa. PMID: 23882135
    4. The p.H557Y mutation in PDE6B, was homozygous in four patients and heterozygous in nine patients, and it was the most frequent mutation (2.5%) in Korean patients with retinitis pigmentosa. PMID: 23049240
    5. Data indicate the upregulation of RREB1, PDE6B, and CD209 suggests that these proteins might play important roles in the differentiation of primitive gut tube cells from embryonic stem cells (hESCs) and in primitive gut tube development into pancreas. PMID: 21792086
    6. Mutations have been identified in the beta-subunit of rod phosphodiesterase in consanguineous Pakistani families with autosomal recessive retinitis pigmentosa. PMID: 21655355
    7. Sp4 is a strong activator of transcription from the beta-PDE promoter PMID: 11943774
    8. the rod cGMP-phosphodiesterase beta-subunit gene is transcriptionally and post-transcriptionally regulated [review] PMID: 17249578
    9. Clinical and genetic characterization of a Chinese family with PDE6B is reported. PMID: 18188951
    10. PDE6B genes and the phenotypic heterogeneity and particularly the severe ocular affection first observed in one Usher syndrome patient. PMID: 18854872
    11. These studies indicate that the 3' UTR of the PDEbeta mRNA is involved in the complex regulation of this gene's expression in the retina. PMID: 19218616

    顯示更多

    收起更多

  • 相關疾病:
    Retinitis pigmentosa 40 (RP40); Night blindness, congenital stationary, autosomal dominant 2 (CSNBAD2)
  • 亞細胞定位:
    Membrane; Lipid-anchor.
  • 蛋白家族:
    Cyclic nucleotide phosphodiesterase family
  • 數據庫鏈接:

    HGNC: 8786

    OMIM: 163500

    KEGG: hsa:5158

    STRING: 9606.ENSP00000420295

    UniGene: Hs.623810



主站蜘蛛池模板: 男女高潮喷水在线观看| 精品国产无套在线观看| 大香伊蕉在人线免费视频| а√最新版在线天堂| 国产96在线 | 亚洲| 美女露出奶头扒开尿口免费网站| 亚洲综合小说另类图片五月天| 日本护士xxxxhd少妇| 精品无码国产自产拍在线观看| 国产午夜视频在线观看| 无码人妻丰满熟妇啪啪7774| 18成禁人视频免费| 久久久国产精品黄毛片| julia无码中文字幕一区| 国产精品色无码av在线观看| 中文字幕精品亚洲无线码vr | 色播久久人人爽人人爽人人片av| 亚洲熟妇无码av另类vr影视| 国产饥渴孕妇在线播放| 老头边吃奶边弄进去呻吟| 10000部拍拍拍免费视频| 国产精品综合一区二区三区| 亚洲男男无套gv大学生| 夜夜高潮夜夜爽国产伦精品| 久久综合亚洲色hezyo国产 | 大陆精大陆国产国语精品 | 清纯小美女主播流白浆| 国产精品久线在线观看| 国产欧美二区综合| 日本老熟妇乱子伦视频| 成人爽a毛片免费| 午夜理论片yy8860y影院| 国产欧美另类精品久久久| 少妇激情艳情综合小视频| 四虎精品成人免费视频| 亚洲a成人无码网站在线| 人人超碰人人超级碰国| 99久久99久久精品国产片果冻| 国产高清狼人香蕉在线| 中老年熟妇激情啪啪大屁股| 国产丰满老熟妇乱xxx1区|