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  4. PDE4DIP Antibody

PDE4DIP Antibody

  • 中文名稱：
    PDE4DIP兔多克隆抗體
  • 貨號：
    CSB-PA716571ESR1HU
  • 規格：
    ￥440
  • 圖片：
    • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA716571ESR1HU at dilution of 1:100
    • Immunohistochemistry of paraffin-embedded human kidney tissue using CSB-PA716571ESR1HU at dilution of 1:100
  • 其他：

產品詳情

  • 產品名稱：
    Rabbit anti-Homo sapiens (Human) PDE4DIP Polyclonal antibody
  • Uniprot No.：
  • 基因名：
  • 別名：
    Cardiomyopathy associated protein 2 antibody; Cardiomyopathy-associated protein 2 antibody; CMYA2 antibody; MMGL antibody; MYOME_HUMAN antibody; Myomegalin antibody; Pde4dip antibody; Phosphodiesterase 4D interacting protein antibody; Phosphodiesterase 4D-interacting protein antibody
  • 宿主：
    Rabbit
  • 反應種屬：
    Human
  • 免疫原：
    Recombinant Human Myomegalin protein (1-310AA)
  • 免疫原種屬：
    Homo sapiens (Human)
  • 標記方式：
    Non-conjugated
  • 克隆類型：
    Polyclonal
  • 抗體亞型：
    IgG
  • 純化方式：
    Antigen Affinity Purified
  • 濃度：
    It differs from different batches. Please contact us to confirm it.
  • 保存緩沖液：
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • 產品提供形式：
    Liquid
  • 應用范圍：
    ELISA, IHC
  • 推薦稀釋比：
    Application Recommended Dilution
    IHC 1:20-1:200
  • Protocols：
  • 儲存條件：
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 貨期：
    Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
  • 用途：
    For Research Use Only. Not for use in diagnostic or therapeutic procedures.

產品評價

靶點詳情

  • 功能：
    Functions as an anchor sequestering components of the cAMP-dependent pathway to Golgi and/or centrosomes.; Participates in microtubule dynamics, promoting microtubule assembly. Depending upon the cell context, may act at the level of the Golgi apparatus or that of the centrosome. In complex with AKAP9, recruits CAMSAP2 to the Golgi apparatus and tethers non-centrosomal minus-end microtubules to the Golgi, an important step for polarized cell movement. In complex with AKAP9, EB1/MAPRE1 and CDK5RAP2, contributes to microtubules nucleation and extension from the centrosome to the cell periphery, a crucial process for directed cell migration, mitotic spindle orientation and cell-cycle progression.
  • 相關疾病：
    A chromosomal aberration involving PDE4DIP may be the cause of a myeloproliferative disorder (MBD) associated with eosinophilia. Translocation t(1;5)(q23;q33) that forms a PDE4DIP-PDGFRB fusion protein.
  • 亞細胞定位：
    Golgi apparatus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome.; [Isoform 13]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton. Golgi apparatus.
  • 組織特異性：
    Highly expressed in adult and fetal heart, in skeletal muscle and, to a lower extent, in brain and placenta.
  • 數據庫鏈接：

    HGNC: 15580

    OMIM: 608117

    KEGG: hsa:653513

    STRING: 9606.ENSP00000358363

    UniGene: Hs.584841



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