PCYOX1 Antibody

說明書

產品詳情

Uniprot No.：

Q9UHG3
基因名：

PCYOX1
別名：

EC 1.8.3.5 antibody; KIAA0908 antibody; PCL1 antibody; PCYOX_HUMAN antibody; PCYOX1 antibody; Prenylcysteine lyase antibody; Prenylcysteine oxidase 1 antibody; Prenylcysteine oxidase precursor antibody
宿主：

Rabbit
反應種屬：

Human,Mouse,Rat
免疫原：

Human PCYOX1
免疫原種屬：

Homo sapiens (Human)
抗體亞型：

IgG
純化方式：

Antigen Affinity purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
產品提供形式：

Liquid
應用范圍：

ELISA,WB,IHC
Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Involved in the degradation of prenylated proteins. Cleaves the thioether bond of prenyl-L-cysteines, such as farnesylcysteine and geranylgeranylcysteine.
基因功能參考文獻：
1. Elevated prenylcysteine oxidase 1 (PCYOX1) activity could help to propagate the oxidative burden of low density lipoproteins (LDLs), thus making PCYOX1 a potential pharmacological target and a new biomarker in cardiovascular disease [Review]. PMID: 28930587
2. initial studies of the kinetic mechanism and stereospecificity of this unusual enzyme PMID: 12186880
3. Addition of the substrate farnesylcysteine to lipoprotein resulted in a time-dependent generation of H(2)O(2) which was stronger in very low density lipoprotein (VLDL) than in LDL or HDL, reflecting the greater protein content of PCL1 in VLDL. PMID: 19253276
亞細胞定位：

Lysosome.
蛋白家族：

Prenylcysteine oxidase family
組織特異性：

Ubiquitous.
數據庫鏈接：

HGNC: 20588

OMIM: 610995

KEGG: hsa:51449

STRING: 9606.ENSP00000387654

UniGene: Hs.567502

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